| Status | 已發表Published |
| Proteases -- From Basic Structure to Function to Drug Design as Targeted Therapy | |
Kwok, H. F. ; Shaw, C.; Walker, B.
| |
| Subtype | 著Authored |
| 2021-12-01 | |
| Publisher | MDPI |
| Publication Place | Switzerland |
| Abstract | In the two last decades, proteases have constituted one of the primary and important targets in drug discovery. The U.S. FDA has approved more than 12 protease therapies in the last 10 years, and a number of next-generation or completely new proteases are under clinical development. Protease inhibition strategies are one of the fastest expanding areas in the field of drugs that show considerable promise. This Special Issue will focus on the recent advances in the discovery and development of protease inhibitors, covering the synthesis of protease inhibitors, the design of new chemical entities acting as inhibitors of special/particular types of proteases, and their mode of actions (Frolova et al. 2020; Slapak et al. 2020; Kunnapuu et al. 2021). In addition, the new applications of these interesting compounds/biomolecules and their limitations have been discussed and described (Wang et al. 2020; Bartosova-Sojkova et al, 2021) |
| Keyword | Protease inhibitor Drug discovery Mode of actions |
| ISBN | 9783036525754 |
| Language | 英語English |
| The Source to Article | PB_Publication |
| PUB ID | 63226 |
| Document Type | Book |
| Collection | DEPARTMENT OF BIOMEDICAL SCIENCES |
| Corresponding Author | Kwok, H. F. |
| Recommended Citation GB/T 7714 | Kwok, H. F.,Shaw, C.,Walker, B.. Proteases -- From Basic Structure to Function to Drug Design as Targeted Therapy[M]. Switzerland:MDPI, 2021. |
| APA | Kwok, H. F.., Shaw, C.., & Walker, B. (2021). Proteases -- From Basic Structure to Function to Drug Design as Targeted Therapy. MDPI. |
| Files in This Item: | There are no files associated with this item. | |||||
Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.
Edit Comment