| Residential College | false |
| Status | 已發表Published |
| Imaging nucleus viscosity and G-quadruplex DNA in living cells using a nucleus-targeting two-photon fluorescent probe | |
Sun, Wan1 ; Cui, Jing-Xue1; Ma, Le-Le1; Lu, Zhong-Lin1; Gong, Bing1; He, Lan2; Wang, Ruibing3
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| 2018-12-07 | |
| Source Publication | ANALYST
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| ISSN | 0003-2654 |
| Volume | 143Issue:23Pages:5799-5804 |
| Abstract | A two-photon fluorescent probe, TP-2Bz, was designed and synthesized and it exhibited good targeting capabilities toward cell nuclei. In particular, TP-2Bz demonstrated a high selectivity to both G-quadruplex DNA and viscosity inside the nucleus with significant ratiometric enhancement in fluorescence, providing a specific, versatile imaging tool for analyzing the viscosity and G-quadruplex DNA in living cells. |
| DOI | 10.1039/c8an01643g |
| URL | View the original |
| Indexed By | SCIE |
| Language | 英語English |
| WOS Research Area | Chemistry ; Electrochemistry ; Instruments & Instrumentation |
| WOS Subject | Chemistry, Analytical ; Electrochemistry ; Instruments & Instrumentation |
| WOS ID | WOS:000450658000018 |
| Publisher | ROYAL SOC CHEMISTRY |
| Scopus ID | 2-s2.0-85056598135 |
| Fulltext Access | |
| Citation statistics | |
| Document Type | Journal article |
| Collection | DEPARTMENT OF PHARMACEUTICAL SCIENCES Institute of Chinese Medical Sciences THE STATE KEY LABORATORY OF QUALITY RESEARCH IN CHINESE MEDICINE (UNIVERSITY OF MACAU) |
| Corresponding Author | Sun, Wan; Lu, Zhong-Lin; He, Lan; Wang, Ruibing |
| Affiliation | 1.Key Laboratory of Radiopharmaceuticals, Ministry of Education, College of Chemistry, Beijing Normal University, Xinjiekouwai Street 19, Beijing, 100875, China 2.National Institute for Food and Drug Control, Beijing, 100050, China 3.State Key Laboratory of Quality Research in Chinese Medicine, and Institute of Chinese Medical Sciences, University of Macau, Taipa, Macao |
| Corresponding Author Affilication | Institute of Chinese Medical Sciences |
| Recommended Citation GB/T 7714 | Sun, Wan,Cui, Jing-Xue,Ma, Le-Le,et al. Imaging nucleus viscosity and G-quadruplex DNA in living cells using a nucleus-targeting two-photon fluorescent probe[J]. ANALYST, 2018, 143(23), 5799-5804. |
| APA | Sun, Wan., Cui, Jing-Xue., Ma, Le-Le., Lu, Zhong-Lin., Gong, Bing., He, Lan., & Wang, Ruibing (2018). Imaging nucleus viscosity and G-quadruplex DNA in living cells using a nucleus-targeting two-photon fluorescent probe. ANALYST, 143(23), 5799-5804. |
| MLA | Sun, Wan,et al."Imaging nucleus viscosity and G-quadruplex DNA in living cells using a nucleus-targeting two-photon fluorescent probe".ANALYST 143.23(2018):5799-5804. |
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