Bioassay guided study on liver protective components in Penthorum chinense Push

UM > Institute of Chinese Medical Sciences

Status	已發表Published
	Bioassay guided study on liver protective components in Penthorum chinense Push
	Wang, A.; Liu, Q.; Wang, Y. T.; Lin, L.
	2014-10-18
Source Publication	28th International Symposium on the Chemistry of Natural Products Committee
Abstract	Penthorum chinense Pursh (PCP), named Ganhuangcao in Chinese, is a plant from the family of Penthoraceae, which is traditionally used for treatment of liver disease, such as hepatitis B and C, hepatocarcinoma as well as alcoholic/non-alcoholic liver damage1-3. Chemical study on this plant demonstrated that it mainly contained flavonoids, flavone glycosides, phenylpropanoids, organic acids, phenols and steroids4-6. Up to now, the chemical principles of its liver protective activity is still remained unknown. Based on the previous studies, we focused on water soluble components of PCP under the guide of t-BHP induced injury on HL-7702 liver cell model. Using comprehensive chromatography methods, 12 compounds were isolated and identified from the water extract of PCP. Among them, compounds 7 and 12 showed potent liver protective activity. These results could provide us new insight into better development and quality control of this herbal medicine.
Keyword	liver protective Penthorum chinense flavonoids
Language	英語English
The Source to Article	PB_Publication
PUB ID	29010
Document Type	Conference paper
Collection	Institute of Chinese Medical Sciences
Corresponding Author	Lin, L.
Recommended Citation GB/T 7714	Wang, A.,Liu, Q.,Wang, Y. T.,et al. Bioassay guided study on liver protective components in Penthorum chinense Push[C], 2014.
APA	Wang, A.., Liu, Q.., Wang, Y. T.., & Lin, L. (2014). Bioassay guided study on liver protective components in Penthorum chinense Push. 28th International Symposium on the Chemistry of Natural Products Committee.

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