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Targeting immune checkpoint B7-H3 antibody–chlorin e6 bioconjugates for spectroscopic photoacoustic imaging and photodynamic therapy
Zhu, L.; Liu, J.; Zhou, G.; Ng, H.M.; Ang, R.L.; Ma, G; Liu, Y.; Yang, S.; Zhang, F.; Miao, K.; Poon, C. W.; Zhang, X.; Yuan, Z.; Deng, C.; Zhao, Q.
2019-10-15
Source PublicationChemical Communications
ISSN1364-548X
Pages14255-14258
Abstract

In this study, we constructed bioconjugates of targeting immune checkpoint B7-H3 antibody and chlorin e6 to treat non-small cell lung cancer under the guidance of spectroscopic photoacoustic and fluorescence imaging. The B7-H3–Ce6 conjugates could display effective tumor diagnosis and therapy and provide a novel approach for immunotherapy.

KeywordPhototherapy Cancer Molecular Imaging Nanomedicine Photoacoustic Imaging Biomedical Optics Immunotherapy
DOI10.1039/C9CC06839B
URLView the original
Indexed BySCIE
Language英語English
WOS IDWOS:000500001300032
The Source to ArticlePB_Publication
Scopus ID2-s2.0-85075671639
Fulltext Access
Citation statistics
Document TypeJournal article
CollectionDEPARTMENT OF BIOMEDICAL SCIENCES
Faculty of Health Sciences
Corresponding AuthorZhao, Q.
Recommended Citation
GB/T 7714
Zhu, L.,Liu, J.,Zhou, G.,et al. Targeting immune checkpoint B7-H3 antibody–chlorin e6 bioconjugates for spectroscopic photoacoustic imaging and photodynamic therapy[J]. Chemical Communications, 2019, 14255-14258.
APA Zhu, L.., Liu, J.., Zhou, G.., Ng, H.M.., Ang, R.L.., Ma, G., Liu, Y.., Yang, S.., Zhang, F.., Miao, K.., Poon, C. W.., Zhang, X.., Yuan, Z.., Deng, C.., & Zhao, Q. (2019). Targeting immune checkpoint B7-H3 antibody–chlorin e6 bioconjugates for spectroscopic photoacoustic imaging and photodynamic therapy. Chemical Communications, 14255-14258.
MLA Zhu, L.,et al."Targeting immune checkpoint B7-H3 antibody–chlorin e6 bioconjugates for spectroscopic photoacoustic imaging and photodynamic therapy".Chemical Communications (2019):14255-14258.
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