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Recent advances of Rho-associated protein kinase (ROCK) in cardio-cerebrovascular diseases
Ai, N.; Lee, M. Y.; Chong, C. M.; Li, S.
2015-07-01
Source PublicationProgress in Modern Biomedicine
ISSN1671-2285
Pages4198-4200
AbstractRho-associated protein kinase (ROCK) is a member of serine-threonine kinase family that was discovered as a first downstream effector of small GTPase Rho. Some studies have suggested that the abnormal ROCK activation was involved in the pathogenesis of cardiovascular and cerebrovascular diseases. Some small compounds targeting ROCK have been developed and tested in cardiovascular and cerebrovascular diseases clinic models. This review is to introduce the recent advances in the role of ROCK in cardio-cerebrovascular disease and the application of ROCK inhibitors.
KeywordROCK Rho Cardio-cerebrovascular diseases
Language其他語言Others
The Source to ArticlePB_Publication
PUB ID57816
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Corresponding AuthorLee, M. Y.
Recommended Citation
GB/T 7714
Ai, N.,Lee, M. Y.,Chong, C. M.,et al. Recent advances of Rho-associated protein kinase (ROCK) in cardio-cerebrovascular diseases[J]. Progress in Modern Biomedicine, 2015, 4198-4200.
APA Ai, N.., Lee, M. Y.., Chong, C. M.., & Li, S. (2015). Recent advances of Rho-associated protein kinase (ROCK) in cardio-cerebrovascular diseases. Progress in Modern Biomedicine, 4198-4200.
MLA Ai, N.,et al."Recent advances of Rho-associated protein kinase (ROCK) in cardio-cerebrovascular diseases".Progress in Modern Biomedicine (2015):4198-4200.
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