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Epigenetic changes in BRCA1-mutated familial breast cancer
Wang, S. M.
2015-02-04
Source PublicationCancer Genetics
ISSN2210-7762
Pages237-240
Abstract

Familial breast cancer occurs in about 10% of breast cancer cases. Germline mutation in BRCA1 is the most penetrant predisposition for the disease. Mutated BRCA1 leads to disease by causing genome instability via multiple mechanisms including epigenetic changes. This review summarizes recent progress in studying the correlation between BRCA1 predisposition and epigenetic alterations in BRCA1-type familial breast cancer.

KeywordBrca1 Familial Breast Cancer Gremlin Mutation Epigenetic Alteration Autosomal Dominant
DOI10.1016/j.cancergen.2015.02.001
Language英語English
The Source to ArticlePB_Publication
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Document TypeJournal article
CollectionDEPARTMENT OF PUBLIC HEALTH AND MEDICINAL ADMINISTRATION
Faculty of Health Sciences
Corresponding AuthorWang, S. M.
Recommended Citation
GB/T 7714
Wang, S. M.. Epigenetic changes in BRCA1-mutated familial breast cancer[J]. Cancer Genetics, 2015, 237-240.
APA Wang, S. M..(2015). Epigenetic changes in BRCA1-mutated familial breast cancer. Cancer Genetics, 237-240.
MLA Wang, S. M.."Epigenetic changes in BRCA1-mutated familial breast cancer".Cancer Genetics (2015):237-240.
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