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靶向上皮间质转化:中药抗肿瘤转移和器官纤维化新策略
Xiao, Q.W.; Lu, J.; Chen, X. P.
2018-04-01
Source Publication医药导报
ISSN1004-0781
Pages401-409
Abstract

上皮间质转化( EMT) 是上皮细胞失去上皮特征, 获得间质表型的生物学现象, 参与了多种生理病理过程, 尤其是肿瘤转移和器官纤维化。EMT 及其信号通路蕴含着抗肿瘤转移和器官纤维化的潜在药物靶点。从中药中发现 了一些具有抑制 EMT 作用的化合物、提取物及中药复方。该文简述了 EMT 这一生物现象, 并通过查阅 Web of science、 PubMed 等数据库,对中药抑制 EMT 的药理作用与分子机制进行综述,以期为基于 EMT 的创新中药研究提供参考。

KeywordChinese Medicine Emt Fibrosis Metastasis
URLView the original
Language其他語言Others
The Source to ArticlePB_Publication
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Corresponding AuthorChen, X. P.
Recommended Citation
GB/T 7714
Xiao, Q.W.,Lu, J.,Chen, X. P.. 靶向上皮间质转化:中药抗肿瘤转移和器官纤维化新策略[J]. 医药导报, 2018, 401-409.
APA Xiao, Q.W.., Lu, J.., & Chen, X. P. (2018). 靶向上皮间质转化:中药抗肿瘤转移和器官纤维化新策略. 医药导报, 401-409.
MLA Xiao, Q.W.,et al."靶向上皮间质转化:中药抗肿瘤转移和器官纤维化新策略".医药导报 (2018):401-409.
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