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IL-13 基因+ 2044G/A 多态性与哮喘、血浆细胞因子水平间关系
Alternative TitleRelationships among IL-13 gene polymorphism, asthma and plasma cytokine levels
Liu, JL, ; Wu, B, ; Chen, HJ, ; He, C. W., ; Liu, ZH, ; Xie, JX
2004-04-30
Source Publication临床肺科杂志
ISSN1009-6663
Pages122-124
Abstract目的 探讨血浆 Ig E、白细胞介素 13基因 (IL - 13)水平在哮喘以及 IL - 13基因及 2 0 4 4位点具有相同基因型的个体二者的相关性。方法 用聚合酶链反应和限制性片段长度多态性 (PCR/ RFIP)方法检测哮喘对照组 +2 0 4 4位点多态性 ,用酶联免疫吸附法 (EL ISA)测定血浆 Ig E、IL - 13水平。结果  IL - 13基因 +2 0 4 4位点存在三种基因型。在哮喘和对照组 ,同一位点具有相同基因型的个体 ,其细胞因子水平存在显著性差异 ,(P<0 .0 1) ,在哮喘或对照组 ,具有相同基因型的个体 ,其 Ig E及 IL - 13水平存在显著性正相关 (r=0 .5 2~ 0 .6 7,P<0 .0 1~ 0 .0 5 )。结论 Ig E、IL - 13是影响哮喘发病的重要细胞因子 ,且二者存在显著性正相关。
KeywordInterleukin-12 IgE Gene Polyrophism Asthma
Language其他語言Others
The Source to ArticlePB_Publication
PUB ID24808
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Corresponding AuthorWu, B,
Recommended Citation
GB/T 7714
Liu, JL, ,Wu, B, ,Chen, HJ, ,等. IL-13 基因+ 2044G/A 多态性与哮喘、血浆细胞因子水平间关系[J]. 临床肺科杂志, 2004, 122-124.
APA Liu, JL, ., Wu, B, ., Chen, HJ, ., He, C. W., ., Liu, ZH, ., & Xie, JX (2004). IL-13 基因+ 2044G/A 多态性与哮喘、血浆细胞因子水平间关系. 临床肺科杂志, 122-124.
MLA Liu, JL, ,et al."IL-13 基因+ 2044G/A 多态性与哮喘、血浆细胞因子水平间关系".临床肺科杂志 (2004):122-124.
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