Dosimetric study for cervix carcinoma treatmentusing intensity modulated radiation therapy(IMRT) compensation based on 3D intracavitarybrachytherapy technique

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	Dosimetric study for cervix carcinoma treatmentusing intensity modulated radiation therapy(IMRT) compensation based on 3D intracavitarybrachytherapy technique
	Yin, G.; Wang, P.; Lang, J.; Tian, Y.; Luo, Y.; Fan, Z.; Tam, K. Y.
	2016-06-30
Source Publication	Journal of Contemporary Brachytherapy
ISSN	1689-832X
Pages	221-232
Abstract	Purpose: Intensity modulated radiation therapy (IMRT) compensation based on 3D high-dose-rate (HDR) intracavitary brachytherapy (ICBT) boost technique (ICBT + IMRT) has been used in our hospital for advanced cervix carcinoma patients. The purpose of this study was to compare the dosimetric results of the four different boost techniques (the conventional 2D HDR intracavitary brachytherapy [CICBT], 3D optimized HDR intracavitary brachytherapy [OICBT], and IMRT-alone with the applicator in situ). Material and methods: For 30 patients with locally advanced cervical carcinoma, after the completion of external beam radiotherapy (EBRT) for whole pelvic irradiation 45 Gy/25 fractions, five fractions of ICBT + IMRT boost with 6 Gy/fractions for high risk clinical target volume (HRCTV), and 5 Gy/fractions for intermediate risk clinical target volume (IRCTV) were applied. Computed tomography (CT) and magnetic resonance imaging (MRI) scans were acquired using an in situ CT/MRI-compatible applicator. The gross tumor volume (GTV), the high/intermediate-risk clinical target volume (HRCTV/IRCTV), bladder, rectum, and sigmoid were contoured by CT scans. Results: For ICBT + IMRT plan, values of D90, D100 of HRCTV, D90, D100, and V100 of IRCTV significantly increased (p < 0.05) in comparison to OIC
Keyword	brachytherapy cervical cancer cervix carcinoma dosimetry IMRT
URL	View the original
Language	英語English
The Source to Article	PB_Publication
PUB ID	19625
Document Type	Journal article
Collection	DEPARTMENT OF PHARMACEUTICAL SCIENCES
Corresponding Author	Tam, K. Y.
Recommended Citation GB/T 7714	Yin, G.,Wang, P.,Lang, J.,et al. Dosimetric study for cervix carcinoma treatmentusing intensity modulated radiation therapy(IMRT) compensation based on 3D intracavitarybrachytherapy technique[J]. Journal of Contemporary Brachytherapy, 2016, 221-232.
APA	Yin, G.., Wang, P.., Lang, J.., Tian, Y.., Luo, Y.., Fan, Z.., & Tam, K. Y. (2016). Dosimetric study for cervix carcinoma treatmentusing intensity modulated radiation therapy(IMRT) compensation based on 3D intracavitarybrachytherapy technique. Journal of Contemporary Brachytherapy, 221-232.
MLA	Yin, G.,et al."Dosimetric study for cervix carcinoma treatmentusing intensity modulated radiation therapy(IMRT) compensation based on 3D intracavitarybrachytherapy technique".Journal of Contemporary Brachytherapy (2016):221-232.

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