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Patent NumberCN110330503B
Status已授權 Granted
一种化合物、其制备方法及应用以及抗类风湿性关节炎的药物
Year Issued2020
2020-12-08
Application NumberCN201910569463.2
Application Date2019-06-27
Rights Holder澳門大學
何承伟; 屠言贝; 王恺; 张庆文
CountryChina
Subtype发明专利 Invention
Contribution Rank1
Abstract

本发明公开了一种化合物、其制备方法及应用以及抗类风湿性关节炎的药物,涉及天然药物及医药技术领域。化合物为新化合物,可以为烟豆中的9种提取物glytacoumestan A‑I。该制备方法从烟豆中提取该化合物,该化合物在制备类风湿性关节炎药物中的应用,药效试验表明,该coumestan类化合物能够显著缓解脂多糖(LPS)和白细胞介素‑1β(IL‑1β)刺激的细胞炎症反应,并且能够抑制破骨细胞的分化,提示这些化合物用于制备抗类风湿性关节炎药物的应用前景。因此,本发明为研究与开发新的抗类风湿性关节炎药物提供了候选化合物,为综合开发利用烟豆资源提供了科学依据。

Keyword烟豆 类风湿性关节炎 Coumestan
Subject Area中医学与中药学
Funding ProjectStudies on the chemical components and mechanisms for the anti-rheumatoid arthritic activity of Glycine tabacina extract
Language中文Chinese
Open (Notice) NumberCN 110330503 A
Patent Agent魏彦 ; 洪玉姬
Agency成都超凡明远知识产权代理有限公司
Document TypePatent
CollectionInstitute of Chinese Medical Sciences
Corresponding Author何承伟
Affiliation澳門大學
Recommended Citation
GB/T 7714
何承伟,屠言贝,王恺,等. 一种化合物、其制备方法及应用以及抗类风湿性关节炎的药物. CN110330503B[P]. 2020-12-08.
APA 何承伟., 屠言贝., 王恺., & 张庆文 (2019-06-27). 一种化合物、其制备方法及应用以及抗类风湿性关节炎的药物.
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