Status | 已發表Published |
Cucurbit[n]uril-based Nanomaterials for Biomedically Related Applications | |
Wang, R.![]() ![]() | |
2019-04-14 | |
Source Publication | The 9th CASE and 2nd C5 Symposium on Supramolecular Chemistry
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Abstract | Cucurbit[n]urils (CB[n]), an emerging family of macrocyclic molecules, consist of n glycoluril units connected by 2n methylene groups, and they possess not only a hydrophobic internal cavity that can encapsulate various lipophilic guest molecules, but also the two carbonyl-fringed portals that are good cation-receptors. Our research group has been actively investigating CB[n]’s complexations with a variety of drug molecules and biomedically important molecules during the past several years [1-3], from both organic chemistry and pharmaceutical sciences perspectives. Very recently, we have incorporated CB[n]s and their derivatives into a variety of functional nanobiomaterials for controlled payload release [4-6]. We are also attempting to extend relevant studies into other macrocyclic molecules such as cyclodextrins [7], calixarenes and pillararenes to fully leverage the unique physical/chemical properties from each family of these host molecules in the construction of nanobiomaterials. |
Keyword | Cucurbit[n]uril Nanomaterials |
Language | 英語English |
The Source to Article | PB_Publication |
PUB ID | 44767 |
Document Type | Conference paper |
Collection | Institute of Chinese Medical Sciences |
Corresponding Author | Wang, R. |
Recommended Citation GB/T 7714 | Wang, R.. Cucurbit[n]uril-based Nanomaterials for Biomedically Related Applications[C], 2019. |
APA | Wang, R..(2019). Cucurbit[n]uril-based Nanomaterials for Biomedically Related Applications. The 9th CASE and 2nd C5 Symposium on Supramolecular Chemistry. |
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