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Multiwalled Carbon Nanotubes and NaYF4:Yb3+/Er3+ NanoparticleDoped Bilayer Hydrogel for Concurrent NIR-Triggered Drug Release and Up-Conversion Luminescence Tagging
Ziyong Cheng1; Ruitao Chai1,2; Pingan Ma1; Yunlu Dai1,2; Xiaojiao Kang1,2; Hongzhou Lian1; Zhiyao Hou1; Chunxia Li1; Jun Lin1
2013
Source PublicationLangmuir
ISSN0743-7463
Volume29Pages:9573−9580
Abstract

Bilayer thermosensitive P(NIPAm-co-AAm) hydrogel discs were prepared by a facile UV light initiation process from N-isopropylacrylamide (NIPAm) and acrylamide (AAm) monomers’ cross-linking copolymerization. Poly(ethylene glycol) (PEG) as a poreforming agent was added in order to form a porous structure and improve the water content in the hydrogel. Functional materials of NaYF4:Yb3+/Er3+ nanoparticles and multiwalled carbon nanotubes (MWCNTs) were incorporated into different layers of the P(NIPAm-coAAm) hydrogel for the purpose of up-conversion luminescence labeling and the NIR light antenna effect, respectively. Significantly improved drug release from composite hydrogels was achieved in response to 980 nm NIR light irradiation by using lysozyme as a macromolecular drug. The multifunctional hydrogel reported here provides a platform for simultaneous NIR luminescence labeling and NIR-driven drug release

DOI10.1021/la402036p
Indexed BySCIE
Language英語English
WOS Research AreaChemistry ; Materials Science
WOS SubjectChemistry, Multidisciplinary ; Chemistry, Physical ; Materials Science, Multidisciplinary
WOS IDWOS:000322695000032
Scopus ID2-s2.0-84881033906
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Citation statistics
Document TypeJournal article
CollectionFaculty of Health Sciences
Corresponding AuthorJun Lin
Affiliation1.State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, People’s Republic of China
2.University of the Chinese Academy of Sciences, Beijing 100049, People’s Republic of China
Recommended Citation
GB/T 7714		 Ziyong Cheng,Ruitao Chai,Pingan Ma,et al. Multiwalled Carbon Nanotubes and NaYF4:Yb3+/Er3+ NanoparticleDoped Bilayer Hydrogel for Concurrent NIR-Triggered Drug Release and Up-Conversion Luminescence Tagging[J]. Langmuir, 2013, 29, 9573−9580.
APA Ziyong Cheng., Ruitao Chai., Pingan Ma., Yunlu Dai., Xiaojiao Kang., Hongzhou Lian., Zhiyao Hou., Chunxia Li., & Jun Lin (2013). Multiwalled Carbon Nanotubes and NaYF4:Yb3+/Er3+ NanoparticleDoped Bilayer Hydrogel for Concurrent NIR-Triggered Drug Release and Up-Conversion Luminescence Tagging. Langmuir, 29, 9573−9580.
MLA Ziyong Cheng,et al."Multiwalled Carbon Nanotubes and NaYF4:Yb3+/Er3+ NanoparticleDoped Bilayer Hydrogel for Concurrent NIR-Triggered Drug Release and Up-Conversion Luminescence Tagging".Langmuir 29(2013):9573−9580.
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