The theoretical challenges for international relations (IR) posed by China’s rise cannot be adequately addressed at a mere theoretical level. Predicated on a Cartesian/Newtonian ontology that assumes a mechanistic world made up of discrete, self-contained parts (e.g., sovereign nation-states), mainstream IR theories offer limited understanding of China’s rise. In this article, I propose an alternative, holographic relational ontology. Drawing upon recent IR scholarship on relational ontology and holographic ideas in quantum physics as well as traditional Asian thoughts, this ‘new’ ontology posits that the world exists fundamentally as holographic relations, in which a part is a microcosmic reflection of its larger whole(s). As a part of various wholes in global politics, ‘China’ is thus never an entity in and of itself, but holographic reflections of them. Its rise is best understood as a phenomenon of holographic transition, in which characteristics of those larger wholes are being enfolded into what is known as ‘China’. Thus, both the ‘China’ challenges and ‘China’ opportunities, rather than some inherently ‘Chinese’ properties, are products of China’s holographic relations. This ontology has broader conceptual and methodological as well as policy implications for IR in East Asia and beyond.