甘西鼠尾草中丹参二醇B抑制血管新生活性研究

UM > Institute of Chinese Medical Sciences

Residential College	false
Status	已發表Published
	甘西鼠尾草中丹参二醇B抑制血管新生活性研究
	庄文婷 1; 朱路平 1; 向诚 1; 何静 1; 李鵬2 ; 李宝才 1
	2014-06
Source Publication	中成药
Volume	36 Issue:6 Pages:1146-1150
Abstract	AIM: To study the effect of tanshindiol B from Salvia przewalskii Maxim. on angiogenic activity. METHOD: Tanshindiol B was isolated from acetonic extract of S. przewalskii and purified by the silica gel column and Sephadex LH-20 column chromatography. MTT method was employed to explore the effect of tanshindiol B on the migration and the expression of human umbilical vein endothelial cells (HUVEC) and to measure the vascular endothelial growth factor (VEGF) level. The chicken chorioallantoic membrane (CAM) model was used for in vivo inhibition of angiogenic activity. RESULTS: Tanshindiol B could inhibit the proliferation and migration of HUVEC, angiogenesis on CAM, and the secrete of VEGF in a dose-dependent manner. CONCLUSION: Tanshindiol B possesses the anti-angiogenic activity, so it can be a promising candidate for angiogenesis inhibitors.
Document Type	Journal article
Collection	Institute of Chinese Medical Sciences
Corresponding Author	李鵬; 李宝才
Affiliation	1.Kunming University of Science and Technology 2.University of macau
Corresponding Author Affilication	University of Macau
Recommended Citation GB/T 7714	庄文婷,朱路平,向诚,等. 甘西鼠尾草中丹参二醇B抑制血管新生活性研究[J]. 中成药, 2014, 36(6), 1146-1150.
APA	庄文婷., 朱路平., 向诚., 何静., 李鵬., & 李宝才 (2014). 甘西鼠尾草中丹参二醇B抑制血管新生活性研究. 中成药, 36(6), 1146-1150.
MLA	庄文婷,et al."甘西鼠尾草中丹参二醇B抑制血管新生活性研究".中成药 36.6(2014):1146-1150.

Files in This Item:
There are no files associated with this item.

If you have any objections to this item, please fill out the form below and the administrator will contact you as soon as possible.
Content:
Email：	*
Affiliation No.
Verification Code:	Refresh

Any comments and suggestions are welcomed.
Title:	*
Content:
Email：	*
Verification Code:	Refresh