| Status | 已發表Published |
| Regulatory T cells, Th17 cells and TLRs: implication for autoimmunity and cancer (review) | |
Chen, X.  ; Oppenheim, J.
| |
| 2009 | |
| Source Publication | Pathway
 |
| ISSN | 1929-1418 |
| Pages | 2-5 |
| Abstract | The Th1/Th2 paradigm of T helper cell subsets has evolved with the identification of distinct lineages of immunosuppressive CD4+FoxP3+ T regulatory cells (Tregs) and pro-inflammatory IL-17- producing T cells (Th17). Upon recognition of pathogen-derived and endogenous ligands, toll-like receptors (TLRs) directly and indirectly regulate the function of Th1 and Th2 cells, but also of Tregs and Th17 cells. Here we review recent findings which have increased our appreciation of the crucial role of Tregs, Th17, and their regulation by TLRs in the immunopathogenesis of autoimmunity as well as cancer. |
| Keyword | Regulatory T cells Th17 cells TLRs |
| URL | View the original |
| Language | 英語English |
| The Source to Article | PB_Publication |
| PUB ID | 34930 |
| Document Type | Journal article |
| Collection | Institute of Chinese Medical Sciences |
| Corresponding Author | Chen, X. |
| Recommended Citation GB/T 7714 | Chen, X.,Oppenheim, J.. Regulatory T cells, Th17 cells and TLRs: implication for autoimmunity and cancer (review)[J]. Pathway, 2009, 2-5. |
| APA | Chen, X.., & Oppenheim, J. (2009). Regulatory T cells, Th17 cells and TLRs: implication for autoimmunity and cancer (review). Pathway, 2-5. |
| MLA | Chen, X.,et al."Regulatory T cells, Th17 cells and TLRs: implication for autoimmunity and cancer (review)".Pathway (2009):2-5. |
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