Residential College | true |
Status | 已發表Published |
Moderate Intensity Static Magnetic Fields Prevent Thrombus Formation in Rats and Mice | |
Zheng, W. | |
2021-03-01 | |
Conference Name | 5th Symposium on Biomedical Sciences for Students, Postdoctoral Fellows and Research Assistants 2021 |
Source Publication | 5th Symposium on Biomedical Sciences for Students, Postdoctoral Fellows and Research Assistants 2021 |
Conference Date | 2021-03 |
Conference Place | - |
Abstract | We established three types of thrombosis models to explore the effects of the static magnetic field (SMF) on thrombosis in rats and mice with three different MF intensities. In the carrageenin-induced thrombosis model in rats, the SMF treatments reduced the black tail length of rats, extracorporeal thrombus, and the mass of wet and dry thrombus, and improved the coagulation index value. However, In FeCl3-induced arterial thrombosis model in rats, the SMF treatment showed some anti-thrombotic effects. More specifically, the SMF treatment affected rodent blood pressure, plasma plasminogen activator inhibitor, tissue-type plasminogen activator, thrombus mass, and thrombus protein content. But In the adrenaline-induced thrombosis model in mice, the SMF treatment had certain effects on the diameter and blood flow velocity of mouse auricle microcirculation in fine veins and arteries. Overall, the highest MF intensities we tested, is 20-150 mT, which showed a trend of anti-thrombotic effect, indicating that the moderate-intensity SMF might serve as a potential treatment for clot-related diseases in the future. |
Keyword | Smf Clot-related Diseases Rat And Mice |
Language | 英語English |
The Source to Article | PB_Publication |
Document Type | Conference paper |
Collection | DEPARTMENT OF PHARMACEUTICAL SCIENCES Faculty of Health Sciences |
Corresponding Author | Zheng, W. |
Recommended Citation GB/T 7714 | Zheng, W.. Moderate Intensity Static Magnetic Fields Prevent Thrombus Formation in Rats and Mice[C], 2021. |
APA | Zheng, W..(2021). Moderate Intensity Static Magnetic Fields Prevent Thrombus Formation in Rats and Mice. 5th Symposium on Biomedical Sciences for Students, Postdoctoral Fellows and Research Assistants 2021. |
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