Problem: The leverage effect plays an important role in finance. However, the statistical test for the presence of the leverage effect is still lacking study. Approach: In this paper, by using high frequency data, we propose a novel procedure to test if the driving Brownian motion of an It (Formula presented.) semi-martingale is correlated to its volatility (referred to as the leverage effect in financial econometrics) over a long time period. The asymptotic setting is based on observations within a long time interval with the mesh of the observation grid shrinking to zero. We construct a test statistic via forming a sequence of Studentized statistics whose distributions are asymptotically normal over blocks of a fixed time span, and then collect the sequence based on the whole data set of a long time span. Result: The asymptotic behaviour of the Studentized statistics was obtained from the cubic variation of the underlying semi-martingale and the asymptotic distribution of the proposed test statistic under the null hypothesis that the leverage effect is absent was established, and we also show that the test has an asymptotic power of one against the alternative hypothesis that the leverage effect is present. Implications: We conducted extensive simulation studies to assess the finite sample performance of the test statistics, and the results show a satisfactory performance for the test. Finally, we implemented the proposed test procedure to a dataset of the SP500 index. We see that the null hypothesis of the absence of the leverage effect is rejected for most of the time period. Therefore, this provides a strong evidence that the leverage effect is a necessary ingredient in modelling high-frequency data.