| Status | 即將出版Forthcoming |
| Chlorfortunones A and B, Two Sesquiterpenoid Dimers, Possessing Dispiro[4,2,5,2]pentadecane-6,10,14-tren Moiety from Chloranthus fortunei | |
| Wu, Xu Jia1; Cao, Dai1; Chen, Fei Long1; Shen, Rong Sheng1; Gao, Jin2,3; Bai, Li Ping1; Zhang, Wei1; Jiang, Zhi Hong1; Zhu, Guo Yuan1 | |
| 2022-10-04 | |
| Source Publication | ACS Omega
 |
| Volume | 7Issue:39Pages:35063-35068 |
| Abstract | Chlorfortunones A (1) and B (2), two novel sesquiterpenoid dimers, were isolated from the roots of Chloranthus fortunei. Their structures were elucidated by spectroscopic analysis and X-ray diffraction analysis. Compounds 1 and 2 represent a new type of sesquiterpenoid dimer possessing an unprecedented 3/5/6/6/6/5 hexacyclic system with a unique dispiro[4,2,5,2]pentadecane-6,10,14-trien moiety. A plausible biosynthetic pathway of 1 and 2 was proposed. Compound 1 showed transforming growth factor (TGF)-β inhibitory activity in MDA-MB-231 cells. |
| DOI | 10.1021/acsomega.2c03927 |
| URL | View the original |
| Language | 英語English |
| Scopus ID | 2-s2.0-85139463637 |
| Fulltext Access | |
| Citation statistics | |
| Document Type | Journal article |
| Collection | University of Macau |
| Affiliation | 1.State Key Laboratory of Quality Research in Chinese Medicine, Guangdong-Hong Kong-Macao Joint Laboratory of Respiratory Infectious Disease, Macau Institute for Applied Research in Medicine and Health, Macau University of Science and Technology, 999078, Macao 2.Increasepharm(Hengqin) Institute Co., Limited, Natl. Engineering Research Center for Modernization of Traditional Chinese Medicine New DDS Branch, Guangdong Province Engineering Research Center for Aerosol Inhalation Preparation, Zhuhai, 519000, China 3.College of Pharmacy, Jinan University, Guangzhou, 510632, China |
| First Author Affilication | University of Macau |
| Recommended Citation GB/T 7714 | Wu, Xu Jia,Cao, Dai,Chen, Fei Long,et al. Chlorfortunones A and B, Two Sesquiterpenoid Dimers, Possessing Dispiro[4,2,5,2]pentadecane-6,10,14-tren Moiety from Chloranthus fortunei[J]. ACS Omega, 2022, 7(39), 35063-35068. |
| APA | Wu, Xu Jia., Cao, Dai., Chen, Fei Long., Shen, Rong Sheng., Gao, Jin., Bai, Li Ping., Zhang, Wei., Jiang, Zhi Hong., & Zhu, Guo Yuan (2022). Chlorfortunones A and B, Two Sesquiterpenoid Dimers, Possessing Dispiro[4,2,5,2]pentadecane-6,10,14-tren Moiety from Chloranthus fortunei. ACS Omega, 7(39), 35063-35068. |
| MLA | Wu, Xu Jia,et al."Chlorfortunones A and B, Two Sesquiterpenoid Dimers, Possessing Dispiro[4,2,5,2]pentadecane-6,10,14-tren Moiety from Chloranthus fortunei".ACS Omega 7.39(2022):35063-35068. |
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