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Smart stimuli-responsive chitosan hydrogel for drug delivery: A review
Bingren Tian1,3; Jiayue Liu2
Source PublicationInternational Journal of Biological Macromolecules
ISSN0141-8130
2023-03-03
Abstract

Smart stimuli-responsive materials can respond to different signals (pH, temperature, light, electricity, etc.), and they have become a hot research topic for drug delivery. As a polysaccharide polymer with excellent biocompatibility, chitosan can be obtained from diverse natural sources. Chitosan hydrogels with different stimuli-response capabilities are widely applied in the drug delivery field. This review highlights and discusses the research progress on chitosan hydrogels concerning their stimuli-responsive capabilities. The feature of various stimuli-responsive kinds of hydrogels is outlined, and their potential use of drug delivery is summarized. Furthermore, the questions and future development chances of stimuli-responsive chitosan hydrogels are analyzed by comparing the current published literature, and the directions for the intelligent development of chitosan hydrogels are discussed.

KeywordChitosan Drug Delivery Hydrogel Stimuli-response
Language英語English
DOI10.1016/j.ijbiomac.2023.123902
URLView the original
Volume235
Pages123902
WOS IDWOS:000954453900001
WOS SubjectBiochemistry & Molecular Biology ; Chemistry, Applied ; Polymer Science
WOS Research AreaBiochemistry & Molecular Biology ; Chemistry ; Polymer Science
Indexed BySCIE
Scopus ID2-s2.0-85149992563
Fulltext Access
Citation statistics
Document TypeReview article
CollectionInstitute of Chinese Medical Sciences
THE STATE KEY LABORATORY OF QUALITY RESEARCH IN CHINESE MEDICINE (UNIVERSITY OF MACAU)
Co-First AuthorBingren Tian
Corresponding AuthorBingren Tian; Jiayue Liu
Affiliation1.Institute of Medical Sciences, General Hospital of Ningxia Medical University, Yinchuan, Ningxia, 750004, China
2.State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, Macau SAR, 999078, China
3.Key Laboratory of Ningxia Stem Cell and Regenerative Medicine, General Hospital of Ningxia Medical University, Yinchuan, Ningxia, 750004, China
Corresponding Author AffilicationInstitute of Chinese Medical Sciences
Recommended Citation
GB/T 7714
Bingren Tian,Jiayue Liu. Smart stimuli-responsive chitosan hydrogel for drug delivery: A review[J]. International Journal of Biological Macromolecules, 2023, 235, 123902.
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