Parkinson's disease is a common mental disease in the world, especially in the middle-aged and elderly groups. Today, clinical diagnosis is the main diagnostic method of Parkinson's disease, but the diagnosis results are not ideal, especially in the early stage of the disease. In this paper, a Parkinson's auxiliary diagnosis algorithm based on a hyperparameter optimization method of deep learning is proposed for the Parkinson's diagnosis. The diagnosis system uses ResNet50 to achieve feature extraction and Parkinson's classification, mainly including speech signal processing part, algorithm improvement part based on Artificial Bee Colony algorithm (ABC) and optimizing the hyperparameters of ResNet50 part. The improved algorithm is called Gbest Dimension Artificial Bee Colony algorithm (GDABC), proposing “Range pruning strategy” which aims at narrowing the scope of search and “Dimension adjustment strategy” which is to adjust gbest dimension by dimension. The accuracy of the diagnosis system in the verification set of Mobile Device Voice Recordings at King's College London (MDVR-CKL) dataset can reach more than 96%. Compared with current Parkinson's sound diagnosis methods and other optimization algorithms, our auxiliary diagnosis system shows better classification performance on the dataset within limited time and resources.