MiRNA 在防治非小细胞肺癌中的研究进展

UM > Faculty of Health Sciences > DEPARTMENT OF BIOMEDICAL SCIENCES

Status	已發表Published
	MiRNA 在防治非小细胞肺癌中的研究进展
Alternative Title	Research Progress of microRNA in Revention and Treatment of Non-small Cell Lung Cancer
	Liu, J.; Wan, X.; Lv, W.; Li, J.; Zhao, Q.
	2015-04-01
Source Publication	现代生物医学进展
ISSN	1673-6273
Pages	1966-1970
Abstract	microRNAs (miRNA) are a class of small non-coding nucleotides, about 22 nucleot-ides in length. MicroRNAs can regulate gene expression through translational repression at post-transcriptional level. Non-small cell lung cancers (NSCLC) account for 80% of all lung cancers. The patient is usually diagnosed at the late phage so that its treatment effeciancy is poor. And it has some characteristics such as poor early diagnosis, easy relapse after treatment, and poor prognosis. Currently therapies mainly used in the treatment of NSCLC are urgery, adiotherapy, chemotherapy, traditional Chinese medicine and biological immunotherapy. The overall treatment effect is not obvious, and the mortality is high. In recent years, a large number of studies have shown that microRNA plays an important role in cancer development, metastasis and recurrence, but yet researchers haven't established a system specification of microRNAs to standardize the diagnosis, treatment and prognosis of NSCLC, and the clinical implementation is difficult. In this paper, we review the newly published studies about miRNAs in NSCLC diagnosis, treatment and prognosis, hoping that miRNAs may have clinical therapeutic uses in human diseases.
Keyword	microRNA 非小细胞肺癌(NSCLC) 诊断治疗预后
URL	View the original
Language	其他語言Others
The Source to Article	PB_Publication
PUB ID	55350
Document Type	Journal article
Collection	DEPARTMENT OF BIOMEDICAL SCIENCES
Corresponding Author	Zhao, Q.
Recommended Citation GB/T 7714	Liu, J.,Wan, X.,Lv, W.,等. MiRNA 在防治非小细胞肺癌中的研究进展[J]. 现代生物医学进展, 2015, 1966-1970.
APA	Liu, J.., Wan, X.., Lv, W.., Li, J.., & Zhao, Q. (2015). MiRNA 在防治非小细胞肺癌中的研究进展. 现代生物医学进展, 1966-1970.
MLA	Liu, J.,et al."MiRNA 在防治非小细胞肺癌中的研究进展".现代生物医学进展 (2015):1966-1970.

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