This paper aims to investigate the second-hand luxury omni-channel trade business through reviewing global and Chinese literatures and case studies to help understand the industry development opportunities for Macau business. Through studying the successful industrial leaders on their omni-channel strategy with a resource based view model and combining with the local industrial situation in Macau, the study will provide analysis and strategic suggestions for local operator P-company. Both primary and secondary data from industrial practitioners and related local parties are examined and discussed. The study can also be considered as a helpful reference to other second-hand luxury retailers in Macau because limited relevant studies was conducted in the local field prior to this and very limited local market information is organised for business operators to access. At the same time, second-hand luxury business from similar Chinese tourist focused destinations in Asia such as Hong Kong, Bangkok, Singapore, and etc. can also benefit from the study with relevant insights for strategic considerations.