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Umbrella review of time-restricted eating on weight loss, fasting blood glucose, and lipid profile
Chew, Han Shi Jocelyn1; Ang, Wei How Darryl1; Tan, Zhen Yang Abel1; Ang, Wen Wei1; Chan, Kin Sun2; Lau, Ying1
2023-09-01
Source PublicationNutrition Reviews
ISSN0029-6643
Volume81Issue:9Pages:1180-1199
AbstractContext: A growing number of systematic reviews with meta-analyses have examined the effectiveness of time-restricted eating (TRE) in reducing weight and improving fasting blood glucose and lipid profiles. However, mixed results have been found, and its effectiveness remains uncertain. Objective: This umbrella review aimed to summarize systematic reviews that (1) examine the effects of TRE on weight loss, fasting blood glucose, total cholesterol, triglycerides, high-density-lipoprotein cholesterol (HDL-C) and low-density-lipoprotein cholesterol (LDL-C) in individuals with overweight and obesity; and (2) compare the effect sizes on these outcomes between conventional TRE and Ramadan fasting. Data Sources: A total of 11 databases were searched from inception until March 11, 2022. Data Extraction: Two independent reviewers performed article selection, data extraction, and quality assessment. Data Analysis: Seven systematic reviews with 30 unique meta-analyses involving 7231 participants from 184 primary studies were included. The quality of each review was evaluated as moderate (14.3%) or critically low (85.7%) according to the Assessment of Multiple Systematic Reviews 2. The degree of overlap was rated as slight for all outcomes (corrected cover area = 1.04%-4.27%). Meta-analyses at the meta-data level suggest that TRE is beneficial for reducing weight (P =. 006) and fasting blood glucose (P <. 01). Meta-analyses at the primary study level suggest that the effect on LGL-C was significant (P =. 03). Subgroup analyses revealed greater effects in lowering fasting blood glucose, total cholesterol, and LDL-C from Ramadan fasting than from conventional TRE. The credibility of evidence was rated as suggestive (3.3%), weak (36.7%) or nonsignificant (60%) using a classification method. Conclusion: TRE may complement usual care and reduce body weight and fasting blood glucose. Rigorous randomized controlled trials with long-term assessments in a wide range of populations are warranted.
Keywordfasting blood glucose lipid profile time-restricted eating umbrella review weight
DOI10.1093/nutrit/nuac103
URLView the original
Language英語English
Scopus ID2-s2.0-85163899455
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Document TypeJournal article
CollectionUniversity of Macau
Affiliation1.Alice Lee Centre for Nursing Studies, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
2.Department of Government and Public Administration, University of Macau, Macao
Recommended Citation
GB/T 7714
Chew, Han Shi Jocelyn,Ang, Wei How Darryl,Tan, Zhen Yang Abel,et al. Umbrella review of time-restricted eating on weight loss, fasting blood glucose, and lipid profile[J]. Nutrition Reviews, 2023, 81(9), 1180-1199.
APA Chew, Han Shi Jocelyn., Ang, Wei How Darryl., Tan, Zhen Yang Abel., Ang, Wen Wei., Chan, Kin Sun., & Lau, Ying (2023). Umbrella review of time-restricted eating on weight loss, fasting blood glucose, and lipid profile. Nutrition Reviews, 81(9), 1180-1199.
MLA Chew, Han Shi Jocelyn,et al."Umbrella review of time-restricted eating on weight loss, fasting blood glucose, and lipid profile".Nutrition Reviews 81.9(2023):1180-1199.
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