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Innovative Strategies for Hair Regrowth and Skin Visualization
Mai, Qiuying1; Han, Yanhua1; Cheng, Guopan2; Ma, Rui2; Yan, Zhao2; Chen, Xiaojia3; Yu, Guangtao4; Chen, Tongkai2; Zhang, Shu1
2023-04-01
Source PublicationPharmaceutics
Volume15Issue:4
AbstractToday, about 50% of men and 15–30% of women are estimated to face hair-related problems, which create a significant psychological burden. Conventional treatments, including drug therapy and transplantation, remain the main strategies for the clinical management of these problems. However, these treatments are hindered by challenges such as drug-induced adverse effects and poor drug penetration due to the skin’s barrier. Therefore, various efforts have been undertaken to enhance drug permeation based on the mechanisms of hair regrowth. Notably, understanding the delivery and diffusion of topically administered drugs is essential in hair loss research. This review focuses on the advancement of transdermal strategies for hair regrowth, particularly those involving external stimulation and regeneration (topical administration) as well as microneedles (transdermal delivery). Furthermore, it also describes the natural products that have become alternative agents to prevent hair loss. In addition, given that skin visualization is necessary for hair regrowth as it provides information on drug localization within the skin’s structure, this review also discusses skin visualization strategies. Finally, it details the relevant patents and clinical trials in these areas. Together, this review highlights the innovative strategies for skin visualization and hair regrowth, aiming to provide novel ideas to researchers studying hair regrowth in the future.
Keywordhair regrowth microneedles natural products regenerative medicine skin visualization
DOI10.3390/pharmaceutics15041201
URLView the original
Language英語English
Scopus ID2-s2.0-85154595670
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Document TypeJournal article
CollectionUniversity of Macau
Affiliation1.Guangdong Provincial Key Laboratory of Advanced Drug Delivery Systems, Center for New Drug Research and Development, Guangdong Pharmaceutical University, Guangzhou, 510006, China
2.Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, 510405, China
3.State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, 999078, Macao
4.Stomatological Hospital, Southern Medical University, Guangzhou, 510280, China
Recommended Citation
GB/T 7714
Mai, Qiuying,Han, Yanhua,Cheng, Guopan,et al. Innovative Strategies for Hair Regrowth and Skin Visualization[J]. Pharmaceutics, 2023, 15(4).
APA Mai, Qiuying., Han, Yanhua., Cheng, Guopan., Ma, Rui., Yan, Zhao., Chen, Xiaojia., Yu, Guangtao., Chen, Tongkai., & Zhang, Shu (2023). Innovative Strategies for Hair Regrowth and Skin Visualization. Pharmaceutics, 15(4).
MLA Mai, Qiuying,et al."Innovative Strategies for Hair Regrowth and Skin Visualization".Pharmaceutics 15.4(2023).
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