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Classifying mass spectral data using SVM and wavelet-based feature extraction
Wong Liyen1; Maybin K. Muyeba1; John A. Keane2; Zhiguo Gong3; Valerie Edwards-Jones4
2013
Conference Name9th International Conference on Active Media Technology (AMT)
Source PublicationLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume8210 LNCS
Pages413-422
Conference DateOCT 29-31, 2013
Conference PlaceMaebashi, JAPAN
Abstract

The paper investigates the use of support vector machines (SVM) in classifying Matrix-Assisted Laser Desorption Ionisation (MALDI) Time Of Flight (TOF) mass spectra. MALDI-TOF screening is a simple and useful technique for rapidly identifying microorganisms and classifying them into specific subtypes. MALDI-TOF data presents data analysis challenges due to its complexity and inherent data uncertainties. In addition, there are usually large mass ranges within which to identify the spectra and this may pose problems in classification. To deal with this problem, we use Wavelets to select relevant and localized features. We then search for best optimal parameters to choose an SVM kernel and apply the SVM classifier. We compare classification accuracy and dimensionality reduction between the SVM classifier and the SVM classifier with wavelet-based feature extraction. Results show that wavelet-based feature extraction improved classification accuracy by at least 10%, feature reduction by 76% and runtime by over 80%.

KeywordFeature Reduction Maldi-tof Parameter Search Svm Wavelets
DOI10.1007/978-3-319-02750-0_44
URLView the original
Indexed ByCPCI-S
Language英語English
WOS Research AreaComputer Science
WOS SubjectComputer Science, Information Systems ; Computer Science, Theory & Methods
WOS IDWOS:000340557500044
Scopus ID2-s2.0-84893972924
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Document TypeConference paper
CollectionDEPARTMENT OF COMPUTER AND INFORMATION SCIENCE
Affiliation1.School of Computing, Mathematics and Digital Technology
2.School of Computer Science, University of Manchester, UK
3.Faculty of Science and Technology University of Macau, China
4.Institute for Biomedical Research into Human Movement and Health Manchester Metropolitan University, UK
Recommended Citation
GB/T 7714
Wong Liyen,Maybin K. Muyeba,John A. Keane,et al. Classifying mass spectral data using SVM and wavelet-based feature extraction[C], 2013, 413-422.
APA Wong Liyen., Maybin K. Muyeba., John A. Keane., Zhiguo Gong., & Valerie Edwards-Jones (2013). Classifying mass spectral data using SVM and wavelet-based feature extraction. Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), 8210 LNCS, 413-422.
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