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A highly parallel algorithm for simulating the elastodynamics of a patient-specific human heart with four chambers using a heterogeneous hyperelastic model
Jiang, Yi1,2; Yan, Zhengzheng1,2; Wang, Xinhong3; Chen, Rongliang1,2; Cai, Xiao Chuan4
2024-04-21
Source PublicationJournal of Computational Physics
ISSN0021-9991
Volume508Pages:113027
Abstract

In this paper a highly parallel method is developed for simulating the elastodynamics of a four-chamber human heart with patient-specific geometry. The heterogeneous hyperelastic model is discretized by a finite element method in space and a fully implicit adaptive method in time, and the resulting nonlinear algebraic systems are solved by a scalable domain decomposition algorithm. The deformations of the cardiac muscles are quite complex due to the realistic geometry, the heterogeneous hyperelasticity of the cardiac tissue, and the myocardial fibers with active stresses. Moreover, the deformations in different chambers and at different phases of the cardiac cycle are very different. To simulate all the muscle movements including the atrial diastole, the atrial systole, the isovolumic contraction, the ventricular ejection, the isovolumic relaxation, and the ventricular filling, the temporal-spatial mesh needs to be sufficiently fine, but not too fine so that the overall computing time is manageable, we introduce a baseline mesh in space and a two-level time stepping strategy including a uniform baseline time step size to obtain the desired time accuracy and an adaptive time stepping method within a baseline time step to guarantee the convergence of the nonlinear solver. Through numerical experiments, we investigate the performance of the proposed method with respect to the material coefficients, the fiber orientations, as well as the mesh sizes and the time step sizes. For an unstructured tetrahedral mesh with more than 200 million degree of freedoms, the method scales well for up to 16,384 processor cores for all steps of an entire cardiac cycle.

KeywordDomain Decomposition Finite Element Fully Implicit Method Human Heart Hyperelasticity Model Parallel Computing
DOI10.1016/j.jcp.2024.113027
URLView the original
Indexed BySCIE
Language英語English
WOS Research AreaComputer Science ; Physics
WOS SubjectComputer Science, Interdisciplinary Applications ; Physics, Mathematical
WOS IDWOS:001233546000001
PublisherACADEMIC PRESS INC ELSEVIER SCIENCE, 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495
Scopus ID2-s2.0-85190839991
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Document TypeJournal article
CollectionFaculty of Science and Technology
Corresponding AuthorChen, Rongliang; Cai, Xiao Chuan
Affiliation1.Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China
2.Shenzhen Key Laboratory for Exascale Engineering and Scientific Computing, Shenzhen, China
3.Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China
4.University of Macau, Macau, China
Corresponding Author AffilicationUniversity of Macau
Recommended Citation
GB/T 7714
Jiang, Yi,Yan, Zhengzheng,Wang, Xinhong,et al. A highly parallel algorithm for simulating the elastodynamics of a patient-specific human heart with four chambers using a heterogeneous hyperelastic model[J]. Journal of Computational Physics, 2024, 508, 113027.
APA Jiang, Yi., Yan, Zhengzheng., Wang, Xinhong., Chen, Rongliang., & Cai, Xiao Chuan (2024). A highly parallel algorithm for simulating the elastodynamics of a patient-specific human heart with four chambers using a heterogeneous hyperelastic model. Journal of Computational Physics, 508, 113027.
MLA Jiang, Yi,et al."A highly parallel algorithm for simulating the elastodynamics of a patient-specific human heart with four chambers using a heterogeneous hyperelastic model".Journal of Computational Physics 508(2024):113027.
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