Residential College | false |
Status | 已發表Published |
Multi-contrast learning-guided lightweight few-shot learning scheme for predicting breast cancer molecular subtypes | |
Pan, Xiang1,2; Wang, Pei1; Jia, Shunyuan1; Wang, Yihang1; Liu, Yuan1; Zhang, Yan3; Jiang, Chunjuan4 | |
2024-05 | |
Source Publication | Medical and Biological Engineering and Computing |
ISSN | 0140-0118 |
Volume | 62Issue:5Pages:1601-1613 |
Abstract | Invasive gene expression profiling studies have exposed prognostically significant breast cancer subtypes: normal-like, luminal, HER-2 enriched, and basal-like, which is defined in large part by human epidermal growth factor receptor 2 (HER-2), progesterone receptor (PR), and estrogen receptor (ER). However, while dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) has been generally employed in the screening and therapy of breast cancer, there is a challenging problem to noninvasively predict breast cancer molecular subtypes, which have extremely low-data regimes. In this paper, a novel few-shot learning scheme, which combines lightweight contrastive convolutional neural network (LC-CNN) and multi-contrast learning strategy (MCLS), is worthwhile to be developed for predicting molecular subtype of breast cancer in DCE-MRI. Moreover, MCLS is designed to construct One-vs-Rest and One-vs-One classification tasks, which addresses inter-class similarity among normal-like, luminal, HER-2 enriched, and basal-like. Extensive experiments demonstrate the superiority of our proposed scheme over state-of-the-art methods. Furthermore, our scheme is able to achieve competitive results on few samples due to joint LC-CNN and MCLS for excavating contrastive correlations of a pair of DCE-MRI. |
Keyword | Breast Cancer Few-shot Learning One-vs-one One-vs-rest |
DOI | 10.1007/s11517-024-03031-0 |
URL | View the original |
Indexed By | SCIE |
Language | 英語English |
WOS Research Area | Computer Science ; Engineering ; Mathematical & Computational Biology ; Medical Informatics |
WOS Subject | Computer Science, Interdisciplinary Applications ; Engineering, Biomedical ; Mathematical & Computational Biology ; Medical Informatics |
WOS ID | WOS:001156079100001 |
Publisher | SPRINGER HEIDELBERG, TIERGARTENSTRASSE 17, D-69121 HEIDELBERG, GERMANY |
Scopus ID | 2-s2.0-85184198705 |
Fulltext Access | |
Citation statistics | |
Document Type | Journal article |
Collection | Cancer Centre |
Corresponding Author | Zhang, Yan; Jiang, Chunjuan |
Affiliation | 1.School of Artificial Intelligence and Computer Science, Jiangnan University, Wuxi, China 2.Cancer Center, Faculty of Health Sciences, University of Macau, SAR, Macao 3.Department of Oncology, Wuxi Maternal and Child Health Care Hospital, Jiangnan University, Wuxi, China 4.Department of Nuclear Medicine, Fudan University Shanghai Cancer Center, Shanghai, China |
First Author Affilication | Cancer Centre |
Recommended Citation GB/T 7714 | Pan, Xiang,Wang, Pei,Jia, Shunyuan,et al. Multi-contrast learning-guided lightweight few-shot learning scheme for predicting breast cancer molecular subtypes[J]. Medical and Biological Engineering and Computing, 2024, 62(5), 1601-1613. |
APA | Pan, Xiang., Wang, Pei., Jia, Shunyuan., Wang, Yihang., Liu, Yuan., Zhang, Yan., & Jiang, Chunjuan (2024). Multi-contrast learning-guided lightweight few-shot learning scheme for predicting breast cancer molecular subtypes. Medical and Biological Engineering and Computing, 62(5), 1601-1613. |
MLA | Pan, Xiang,et al."Multi-contrast learning-guided lightweight few-shot learning scheme for predicting breast cancer molecular subtypes".Medical and Biological Engineering and Computing 62.5(2024):1601-1613. |
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