UM  > Faculty of Health Sciences  > Cancer Centre
Residential Collegefalse
Status已發表Published
Multi-contrast learning-guided lightweight few-shot learning scheme for predicting breast cancer molecular subtypes
Pan, Xiang1,2; Wang, Pei1; Jia, Shunyuan1; Wang, Yihang1; Liu, Yuan1; Zhang, Yan3; Jiang, Chunjuan4
2024-05
Source PublicationMedical and Biological Engineering and Computing
ISSN0140-0118
Volume62Issue:5Pages:1601-1613
Abstract

Invasive gene expression profiling studies have exposed prognostically significant breast cancer subtypes: normal-like, luminal, HER-2 enriched, and basal-like, which is defined in large part by human epidermal growth factor receptor 2 (HER-2), progesterone receptor (PR), and estrogen receptor (ER). However, while dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) has been generally employed in the screening and therapy of breast cancer, there is a challenging problem to noninvasively predict breast cancer molecular subtypes, which have extremely low-data regimes. In this paper, a novel few-shot learning scheme, which combines lightweight contrastive convolutional neural network (LC-CNN) and multi-contrast learning strategy (MCLS), is worthwhile to be developed for predicting molecular subtype of breast cancer in DCE-MRI. Moreover, MCLS is designed to construct One-vs-Rest and One-vs-One classification tasks, which addresses inter-class similarity among normal-like, luminal, HER-2 enriched, and basal-like. Extensive experiments demonstrate the superiority of our proposed scheme over state-of-the-art methods. Furthermore, our scheme is able to achieve competitive results on few samples due to joint LC-CNN and MCLS for excavating contrastive correlations of a pair of DCE-MRI.

KeywordBreast Cancer Few-shot Learning One-vs-one One-vs-rest
DOI10.1007/s11517-024-03031-0
URLView the original
Indexed BySCIE
Language英語English
WOS Research AreaComputer Science ; Engineering ; Mathematical & Computational Biology ; Medical Informatics
WOS SubjectComputer Science, Interdisciplinary Applications ; Engineering, Biomedical ; Mathematical & Computational Biology ; Medical Informatics
WOS IDWOS:001156079100001
PublisherSPRINGER HEIDELBERG, TIERGARTENSTRASSE 17, D-69121 HEIDELBERG, GERMANY
Scopus ID2-s2.0-85184198705
Fulltext Access
Citation statistics
Document TypeJournal article
CollectionCancer Centre
Corresponding AuthorZhang, Yan; Jiang, Chunjuan
Affiliation1.School of Artificial Intelligence and Computer Science, Jiangnan University, Wuxi, China
2.Cancer Center, Faculty of Health Sciences, University of Macau, SAR, Macao
3.Department of Oncology, Wuxi Maternal and Child Health Care Hospital, Jiangnan University, Wuxi, China
4.Department of Nuclear Medicine, Fudan University Shanghai Cancer Center, Shanghai, China
First Author AffilicationCancer Centre
Recommended Citation
GB/T 7714
Pan, Xiang,Wang, Pei,Jia, Shunyuan,et al. Multi-contrast learning-guided lightweight few-shot learning scheme for predicting breast cancer molecular subtypes[J]. Medical and Biological Engineering and Computing, 2024, 62(5), 1601-1613.
APA Pan, Xiang., Wang, Pei., Jia, Shunyuan., Wang, Yihang., Liu, Yuan., Zhang, Yan., & Jiang, Chunjuan (2024). Multi-contrast learning-guided lightweight few-shot learning scheme for predicting breast cancer molecular subtypes. Medical and Biological Engineering and Computing, 62(5), 1601-1613.
MLA Pan, Xiang,et al."Multi-contrast learning-guided lightweight few-shot learning scheme for predicting breast cancer molecular subtypes".Medical and Biological Engineering and Computing 62.5(2024):1601-1613.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Pan, Xiang]'s Articles
[Wang, Pei]'s Articles
[Jia, Shunyuan]'s Articles
Baidu academic
Similar articles in Baidu academic
[Pan, Xiang]'s Articles
[Wang, Pei]'s Articles
[Jia, Shunyuan]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Pan, Xiang]'s Articles
[Wang, Pei]'s Articles
[Jia, Shunyuan]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.