Receptor tyrosine kinase-like orphan receptor serves as a potential target in cancer immunotherapy

doi:10.1093/jleuko/qiae141

UM > Faculty of Health Sciences > DEPARTMENT OF BIOMEDICAL SCIENCES

Residential College	false
Status	已發表Published
	Receptor tyrosine kinase-like orphan receptor serves as a potential target in cancer immunotherapy
	Wang, Jiaqi; Li, Zhoufang; Zhao, Qi
	2024-07-08
Source Publication	Journal of leukocyte biology
ISSN	1938-3673
Volume	0 Issue:0 Pages:1-6
Abstract	Receptor tyrosine kinase-like orphan receptor (ROR), consisting of ROR1 and ROR2, is a conserved family of receptor tyrosine kinase superfamily that plays crucial roles during embryonic development with limited expression in adult normal tissues. However, it is overexpressed in a range of hematological malignancies and solid tumors and functions in cellular processes including cell survival, polarity, and migration, serving as a potential target in cancer immunotherapy. This review summarizes the expression and structure of ROR in developmental morphogenesis and its function in cancers associated with Wnt5a signaling and highlights the cancer immunotherapy strategies targeting ROR.
DOI	10.1093/jleuko/qiae141
URL	View the original
Indexed By	SCIE
Fulltext Access	View Full-Text via DOI View Full-Text via Web of Science
Citation statistics
Document Type	Journal article
Collection	DEPARTMENT OF BIOMEDICAL SCIENCES
Corresponding Author	Zhao, Qi
Affiliation	Cancer Centre, Institute of Translational Medicine, Faculty of Health Sciences, University of Macau
Recommended Citation GB/T 7714	Wang, Jiaqi,Li, Zhoufang,Zhao, Qi. Receptor tyrosine kinase-like orphan receptor serves as a potential target in cancer immunotherapy[J]. Journal of leukocyte biology, 2024, 0(0), 1-6.
APA	Wang, Jiaqi., Li, Zhoufang., & Zhao, Qi (2024). Receptor tyrosine kinase-like orphan receptor serves as a potential target in cancer immunotherapy. Journal of leukocyte biology, 0(0), 1-6.
MLA	Wang, Jiaqi,et al."Receptor tyrosine kinase-like orphan receptor serves as a potential target in cancer immunotherapy".Journal of leukocyte biology 0.0(2024):1-6.

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