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Fetal exposure to the Ukraine famine of 1932–1933and adult type 2 diabetes mellitus
LI CHIHUA
2024-08
Source PublicationScience
Pages667-671
AbstractThe short-term impact of famines on death and disease is well documented, but estimating theirpotential long-term impact is difficult. We used the setting of the man-made Ukrainian Holodomorfamine of 1932–1933 to examine the relation between prenatal famine and adult type 2 diabetes mellitus(T2DM). This ecological study included 128,225 T2DM cases diagnosed from 2000 to 2008 among10,186,016 male and female Ukrainians born from 1930 to 1938. Individuals who were born inthe first half-year of 1934, and hence exposed in early gestation to the mid-1933 peak famine period,had a greater than twofold likelihood of T2DM compared with that of unexposed controls. There wasa dose-response relationship between severity of famine exposure and increase in adult T2DM risk.
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
AffiliationInstituteof Chinese Medical Sciences, University of Macau, MacaoSAR 999078, China
First Author AffilicationUniversity of Macau
Recommended Citation
GB/T 7714
LI CHIHUA. Fetal exposure to the Ukraine famine of 1932–1933and adult type 2 diabetes mellitus[J]. Science, 2024, 667-671.
APA LI CHIHUA.(2024). Fetal exposure to the Ukraine famine of 1932–1933and adult type 2 diabetes mellitus. Science, 667-671.
MLA LI CHIHUA."Fetal exposure to the Ukraine famine of 1932–1933and adult type 2 diabetes mellitus".Science (2024):667-671.
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