| Residential College | false |
| Status | 即將出版Forthcoming |
| Medicinal plants and natural products for treating overactive bladder | |
| Chen, Huanxian1; Hoi, Maggie Pui Man1,2; Lee, Simon Ming Yuen1,2,3 | |
| 2024-12-01 | |
| Source Publication | Chinese Medicine (United Kingdom)
 |
| Volume | 19Issue:1 |
| Abstract | Background: Overactive bladder (OAB) presents a high prevalence of 16–18% worldwide. The pathophysiology of OAB is still poorly understood while effective therapy or countermeasure are very limited. On the other hand, medicinal plants and herbal remedies have been utilized for treating lower urinary tract symptoms (LUTS) in both Eastern and Western cultures since ancient times. In recent years, accumulating progress has also been made in OAB treatment research by using medicinal plants. Methods: Relevant literature on the studies of medicinal plants and herbs used to treat OAB was reviewed. The medicinal plants were summarized and categorized into two groups, single-herb medications and herbal formulations. Results: The present review has summarized current understanding of OAB’s pathophysiology, its available treatments and new drug targets. Medicinal plants and natural products which have been used or have shown potential for OAB treatment were updated and comprehensively categorized. Studies on a wide variety of medicinal plants showed promising results, although only a few phytochemicals have been isolated and identified. Until now, none of these herbal compounds have been further developed into clinical therapeutics for OAB. Conclusions: This review provides the basis for discovering and designing new phytopharmaceutical candidates with effective and well-tolerated properties to treat OAB. Increasing evidences indicate new strategies with alternative herbal treatment for OAB have high efficacy and safety, showing great promise for their clinical use. Future studies in a rigorously designed controlled manner will be beneficial to further support the eligibility of herbal treatment as OAB therapeutics. |
| Keyword | Medicinal plants Natural products Overactive bladder |
| DOI | 10.1186/s13020-024-00884-3 |
| URL | View the original |
| Language | 英語English |
| Scopus ID | 2-s2.0-85188796227 |
| Fulltext Access | |
| Citation statistics | |
| Document Type | Journal article |
| Collection | University of Macau |
| Affiliation | 1.State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Science, University of Macau, Macao 2.Department of Pharmaceutical Sciences, Faculty of Health Sciences, University of Macau, Macao 3.Department of Food Science and Nutrition, The Hong Kong Polytechnic University, Hong Kong |
| First Author Affilication | University of Macau |
| Recommended Citation GB/T 7714 | Chen, Huanxian,Hoi, Maggie Pui Man,Lee, Simon Ming Yuen. Medicinal plants and natural products for treating overactive bladder[J]. Chinese Medicine (United Kingdom), 2024, 19(1). |
| APA | Chen, Huanxian., Hoi, Maggie Pui Man., & Lee, Simon Ming Yuen (2024). Medicinal plants and natural products for treating overactive bladder. Chinese Medicine (United Kingdom), 19(1). |
| MLA | Chen, Huanxian,et al."Medicinal plants and natural products for treating overactive bladder".Chinese Medicine (United Kingdom) 19.1(2024). |
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