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Individualized causal mediation analysis with continuous treatment using conditional generative adversarial networks
Huan, Cheng1; Song, Xinyuan1; Yuan, Hongwei2
2024-08
Source PublicationStatistics and Computing
ISSN0960-3174
Volume34Issue:5Pages:170
Abstract

Traditional methods used in causal mediation analysis with continuous treatment often focus on estimating average causal effects, limiting their applicability in precision medicine. Machine learning techniques have emerged as a powerful approach for precisely estimating individualized causal effects. This paper proposes a novel method called CGAN-ICMA-CT that leverages Conditional Generative Adversarial Networks (CGANs) to infer individualized causal effects with continuous treatment. We thoroughly investigate the convergence properties of CGAN-ICMA-CT and show that the estimated distribution of our inferential conditional generator converges to the true conditional distribution under mild conditions. We conduct numerical experiments to validate the effectiveness of CGAN-ICMA-CT and compare it with four commonly used methods: linear regression, support vector machine regression, decision tree, and random forest regression. The results demonstrate that CGAN-ICMA-CT outperforms these methods regarding accuracy and precision. Furthermore, we apply the CGAN-ICMA-CT model to the real-world Job Corps dataset, showcasing its practical utility. By utilizing CGAN-ICMA-CT, we estimate the individualized causal effects of the Job Corps program on the number of arrests, providing insights into both direct effects and effects mediated through intermediate variables. Our findings confirm the potential of CGAN-ICMA-CT in advancing individualized causal mediation analysis with continuous treatment in precision medicine settings.

KeywordCausal Mediation Analysis Cgan Continuous Treatment Distribution Matching Individualized Causal Effects
DOI10.1007/s11222-024-10484-8
URLView the original
Indexed BySCIE
Language英語English
WOS Research AreaComputer Science ; Mathematics
WOS SubjectComputer Science, Theory & Methods ; Statistics & Probability
WOS IDWOS:001296687300001
PublisherSPRINGER, VAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDS
Scopus ID2-s2.0-85201972496
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Citation statistics
Document TypeJournal article
CollectionFaculty of Science and Technology
DEPARTMENT OF MATHEMATICS
Corresponding AuthorSong, Xinyuan
Affiliation1.Department of Statistics, Chinese University of Hong Kong, Shatin, Hong Kong
2.Department of Mathematics, University of Macau, Taipa, Macao
Recommended Citation
GB/T 7714
Huan, Cheng,Song, Xinyuan,Yuan, Hongwei. Individualized causal mediation analysis with continuous treatment using conditional generative adversarial networks[J]. Statistics and Computing, 2024, 34(5), 170.
APA Huan, Cheng., Song, Xinyuan., & Yuan, Hongwei (2024). Individualized causal mediation analysis with continuous treatment using conditional generative adversarial networks. Statistics and Computing, 34(5), 170.
MLA Huan, Cheng,et al."Individualized causal mediation analysis with continuous treatment using conditional generative adversarial networks".Statistics and Computing 34.5(2024):170.
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