Against the backdrop of escalating resource depletion and the urgent quest for alternative sources, liquefied natural gas (LNG) is increasingly gaining prominence as a sustainable solution, particularly in refrigeration applications. However, its underutilization results in wasted resources. To efficiently harness the released cold energy from LNG gasification, this study proposes an integrated system comprising air separation, power generation, refrigeration, and ice thermal storage. The system undergoes optimization using the non-dominated sorting genetic algorithm II (NSGA-II) to determine the optimal operating parameters. The optimized system is comprehensively analyzed from energy, exergy, economic, and environmental perspectives. Results show that the system, with a 70t/h LNG capacity, achieves an energy efficiency of 42.52% and an exergy efficiency of 48.09%. Economically, the system incurs a cost of approximately 0.0711 $/kWh and can mitigate over 1.4504*10kg⁷ of CO₂ emissions. Compared to traditional LNG utilization systems, the integrated system demonstrates a 22.32% improvement in energy efficiency, a 7.69% enhancement in exergy efficiency, and a cost reduction of 0.0049 $/kWh. In summary, this technologically advanced and economically viable system offers a significant alternative to optimize LNG cold energy utilization.