Natural polysaccharides regulate intestinal microbiota for inhibiting colorectal cancer

doi:10.1016/j.heliyon.2024.e31514

Residential College	false
Status	已發表Published
	Natural polysaccharides regulate intestinal microbiota for inhibiting colorectal cancer
	Liu, Lili 1; Li, Yinan 1; Zheng, Xiaoting 2; Huang, Rong 2,3; Huang, Xiaoli 3; Zhao, Yonghui 1; Liu, Wenjing 3; Lei, Yanli 3; Li, Qiu 3; Zhong, Zhangfeng 2; Zhao, Ziyun 1
	2024-05-30
Source Publication	Heliyon
ISSN	2405-8440
Volume	10 Issue:10
Abstract	The gastrointestinal tract is an important part of the human immune system. The gut microbiome, which constitutes a major component of the gastrointestinal tract, plays a crucial role in maintaining normal physiological functions and influences the development, diagnosis, and immunotherapy of colorectal cancer (CRC). Natural polysaccharides can be extracted from animals, plants, and traditional Chinese medicines. They serve as an essential energy source for the gut microbiome, promoting probiotic proliferation and regulating the intestinal microecological balance. Moreover, polysaccharides exhibit anti-tumor effects due to their immune regulatory functions and low toxicity. This review focuses on discussing these anti-tumor effects in CRC, along with improving gut microbiome dysbiosis and regulating the tumor immune microenvironment, providing evidence for effective therapeutic strategies against CRC.
Keyword	Anti-tumor Colorectal cancer Gut microbiome Natural polysaccharides
DOI	10.1016/j.heliyon.2024.e31514
URL	View the original
Language	英語English
Scopus ID	2-s2.0-85193450343
Fulltext Access	View Full-Text via DOI View Full-Text via Web of Science View Full-Text via Scopus
Citation statistics
Document Type	Journal article
Collection	University of Macau
Affiliation	1.University of Health and Rehabilitation Sciences (Qingdao Central Medical Group), Qingdao, 266000, China 2.Macao Centre for Research and Development in Chinese Medicine, State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao SAR, 999078, China 3.College of Chemistry and Pharmaceutical Sciences, National Joint Local Engineering Laboratory of Agricultural Bio-Pharmaceutical Laboratory, Agricultural University, Qingdao, Qingdao, 266109, China
Recommended Citation GB/T 7714	Liu, Lili,Li, Yinan,Zheng, Xiaoting,et al. Natural polysaccharides regulate intestinal microbiota for inhibiting colorectal cancer[J]. Heliyon, 2024, 10(10).
APA	Liu, Lili., Li, Yinan., Zheng, Xiaoting., Huang, Rong., Huang, Xiaoli., Zhao, Yonghui., Liu, Wenjing., Lei, Yanli., Li, Qiu., Zhong, Zhangfeng., & Zhao, Ziyun (2024). Natural polysaccharides regulate intestinal microbiota for inhibiting colorectal cancer. Heliyon, 10(10).
MLA	Liu, Lili,et al."Natural polysaccharides regulate intestinal microbiota for inhibiting colorectal cancer".Heliyon 10.10(2024).

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