| Residential College | false |
| Status | 已發表Published |
| Peptides for microbe-induced cancers: latest therapeutic strategies and their advanced technologies | |
Lin, Ziqi1,2; Assaraf, Yehuda G.3; Kwok, Hang Fai1,2,4
| |
| 2024-12-01 | |
| Source Publication | Cancer and Metastasis Reviews
 |
| ISSN | 0167-7659 |
| Volume | 43Issue:4Pages:1315-1336 |
| Abstract | Cancer is a significant global health concern associated with multiple distinct factors, including microbial and viral infections. Numerous studies have elucidated the role of microorganisms, such as Helicobacter pylori (H. pylori), as well as viruses for example human papillomavirus (HPV), hepatitis B virus (HBV), and hepatitis C virus (HCV), in the development of human malignancies. Substantial attention has been focused on the treatment of these microorganism- and virus-associated cancers, with promising outcomes observed in studies employing peptide-based therapies. The current paper provides an overview of microbe- and virus-induced cancers and their underlying molecular mechanisms. We discuss an assortment of peptide-based therapies which are currently being developed, including tumor-targeting peptides and microbial/viral peptide-based vaccines. We describe the major technological advancements that have been made in the design, screening, and delivery of peptides as anticancer agents. The primary focus of the current review is to provide insight into the latest research and development in this field and to provide a realistic glimpse into the future of peptide-based therapies for microbe- and virus-induced neoplasms. |
| Keyword | Anticancer agents Microbe- and virus-induced cancers Microbial and viral infections Peptide-based therapeutics |
| DOI | 10.1007/s10555-024-10197-4 |
| URL | View the original |
| Language | 英語English |
| Scopus ID | 2-s2.0-85198656000 |
| Fulltext Access | |
| Citation statistics | |
| Document Type | Journal article |
| Collection | DEPARTMENT OF BIOMEDICAL SCIENCES |
| Affiliation | 1.Cancer Centre, Faculty of Health Sciences, University of Macau, Avenida da Universidade, Taipa, Macao 2.Department of Biomedical Sciences, Faculty of Health Sciences, University of Macau, Avenida da Universidade, Taipa, Macao 3.The Fred Wyszkowski Cancer Research Lab, Faculty of Biology, Technion-Israel Instituteof Technology, Haifa, 3200003, Israel 4.MoE Frontiers Science Center for Precision Oncology, University of Macau, Avenida de Universidade, Taipa, Macao |
| First Author Affilication | Cancer Centre; Faculty of Health Sciences |
| Recommended Citation GB/T 7714 | Lin, Ziqi,Assaraf, Yehuda G.,Kwok, Hang Fai. Peptides for microbe-induced cancers: latest therapeutic strategies and their advanced technologies[J]. Cancer and Metastasis Reviews, 2024, 43(4), 1315-1336. |
| APA | Lin, Ziqi., Assaraf, Yehuda G.., & Kwok, Hang Fai (2024). Peptides for microbe-induced cancers: latest therapeutic strategies and their advanced technologies. Cancer and Metastasis Reviews, 43(4), 1315-1336. |
| MLA | Lin, Ziqi,et al."Peptides for microbe-induced cancers: latest therapeutic strategies and their advanced technologies".Cancer and Metastasis Reviews 43.4(2024):1315-1336. |
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