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Cold Atmospheric Plasma: An Emerging Immunomodulatory Therapy
Liu, Hui1; Liang, Xiaoliu1; Teng, Minglei1; Li, Zhenjie1; Peng, Yisheng1; Wang, Peiyu1; Chen, Hu1; Cheng, Hongwei1,2; Liu, Gang1
2024-05-01
Source PublicationAdvanced Therapeutics
Volume7Issue:5
AbstractCold atmospheric plasma (CAP) is a novel technology that generates a unique combination of reactive oxygen and nitrogen species (ROS/RNS), electric fields, and UV radiation. CAP has shown promise in regulating the immune system and has potential clinical applications in wound healing, cancer treatment, and infection control. This review provides an overview of the immunological regulation activity of CAP, highlighting its substantial impact on cytokines production, immune cell phagocytosis, and immune cell proliferation. CAP has also been demonstrated to have potent therapeutic effect in anti-inflammation, wound repair, viral and bacterial infections. Furthermore, CAP has been investigated as an adjuvant therapy for tumor treatment, eliciting a robust antitumor immune response and remarkable synergistic effects in diverse combination therapies. Further research is needed to fully understand the mechanisms underlying the effects of CAP on the immune system and to optimize its clinical application.
Keywordcold atmospheric plasma combined therapy immunomodulation reactive oxygen species tumor treatment
DOI10.1002/adtp.202300399
URLView the original
Language英語English
Scopus ID2-s2.0-85185109105
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Document TypeJournal article
CollectionUniversity of Macau
Affiliation1.State Key Laboratory of Infectious Disease Vaccine Development, Xiang An Biomedicine Laboratory, National Innovation Platform for Industry-Education Integration in Vaccine Research, State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, 361102, China
2.University of Macau, SAR, 999078, Macao
Recommended Citation
GB/T 7714
Liu, Hui,Liang, Xiaoliu,Teng, Minglei,et al. Cold Atmospheric Plasma: An Emerging Immunomodulatory Therapy[J]. Advanced Therapeutics, 2024, 7(5).
APA Liu, Hui., Liang, Xiaoliu., Teng, Minglei., Li, Zhenjie., Peng, Yisheng., Wang, Peiyu., Chen, Hu., Cheng, Hongwei., & Liu, Gang (2024). Cold Atmospheric Plasma: An Emerging Immunomodulatory Therapy. Advanced Therapeutics, 7(5).
MLA Liu, Hui,et al."Cold Atmospheric Plasma: An Emerging Immunomodulatory Therapy".Advanced Therapeutics 7.5(2024).
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