Brazil-China relationship is two-fold, influencing both economic development and geopolitical strategy in Latin America. On one hand, China views Brazil as an emerging market with abundant natural resources, making sectors such as agriculture, energy, and infrastructure attractive for Chinese investment. On the other hand, Chinese investments often come with infrastructure development projects, such as the Belt and Road Initiative (BRI), which can help Brazil improve its transportation and energy sectors, as seen in the Transoceanic Railway project. Furthermore, the countries have mutually cooperated in other areas, such as in the integration of the BRICS group, the launch of satellites through the China-Brazil Earth Resources Satellite (CBERS) program telecommunications (e.g., 5G technology), the wind energy sector, and green technologies, as well as the integration of Brazil into global value chains. Thus, this study aims to discuss the Sino-Brazilian mutual interests and contribute to the understanding of this broad subject. Our discussions and analyses suggest that it is important for Brazil and China to develop initiatives with mutual and sovereign interests aimed at establishing environmentally sustainable trade with reduced asymmetry. Areas such as the bioeconomy and global governance are of great interest to Brazil and China. The collaborative efforts of these nations can enable new initiatives with prospects to balance forces with the USA. From a macro perspective, the economic and commercial strengthening of BRICS and its relationship with the Global South could serve as a counterpoint to American influence. While BRICS may redefine global power relations, member countries of the group may face influences in managing their regional relations.