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Aggregation-induced emission materials-based Electrochemiluminescence emitters for sensing applications: Progress, challenges and perspectives
WANG XUAN; WAN RONGYAN; TANG YUNQIAN; SUN SHUOYUN; CHEN HONG; LI LINSEN; CHEN JIANLING; WEI JINCHAO; CHI ZHENGUO; LI HAIYIN
2025-02-12
Source PublicationCoordination Chemistry Reviews
Volume531Pages:216520
AbstractDesign and development of electrochemiluminescence (ECL) sensors with high sensitivity and selectivity for analytes quantitative detection plays an important role in monitoring food/environmental safety and preserving human health. Aggregation-induced emission (AIE) materials feature higher luminescence in aggregated state than in dissolved state and hence are considered as ideal emitters to develop high-performance ECL sensors. Enlightened by this, researchers around the world have made considerable efforts to devise and synthesize AIE materials with unique ECL performance for reliably analyzing disease biomarkers and toxic substances with high sensitivity. In this review, we outline the recent advances on devise and preparation of AIE materials with different components exhibiting unique ECL property, and development of AIE materials-based ECL sensors for sensitive detection of nucleic acids, proteins, amino acids, metal ions, anions, etc. Further, the confronting hurdles and perspectives on the future of such ECL sensors were briefly discussed to give the researchers a little inspiration for developing higher-performance sensors. Moreover, we hope this overview will not only facilitate the huge progress of AIE materials-based ECL sensors, but also boost the commercial application in real-life scenarios in the future, truly serving the general public.
KeywordElectrochemiLuminescence Sensoraggregation-induced Emission Materialdisease Biomarkerstoxic Substanceshigher Luminescence
DOI10.1016/j.ccr.2025.216520
URLView the original
Indexed BySCIE
Language英語English
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Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Corresponding AuthorCHEN JIANLING; WEI JINCHAO; LI HAIYIN
Affiliation1.State Key Laboratory of New Pharmaceutical Preparations and Excipients, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of the Ministry of Education, Key Laboratory of Analytical Science and Technology of Hebei Province, College of Chemistry
2.College of Public Health, College of Life Sciences, Hebei University, Baoding 071002, Hebei, China
3.Macau Centre for Research and Development in Chinese Medicine, State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao SAR, 999078, China
4.Luoyang Key Laboratory of Organic Functional Molecules, College of Food and Drug, Luoyang Normal University, Luoyang 471934, Henan, China
5.School of Environmental and Chemical Engineering, Wuyi University, Jiangmen 529020, Guangdong, China
Recommended Citation
GB/T 7714
WANG XUAN,WAN RONGYAN,TANG YUNQIAN,et al. Aggregation-induced emission materials-based Electrochemiluminescence emitters for sensing applications: Progress, challenges and perspectives[J]. Coordination Chemistry Reviews, 2025, 531, 216520.
APA WANG XUAN., WAN RONGYAN., TANG YUNQIAN., SUN SHUOYUN., CHEN HONG., LI LINSEN., CHEN JIANLING., WEI JINCHAO., CHI ZHENGUO., & LI HAIYIN (2025). Aggregation-induced emission materials-based Electrochemiluminescence emitters for sensing applications: Progress, challenges and perspectives. Coordination Chemistry Reviews, 531, 216520.
MLA WANG XUAN,et al."Aggregation-induced emission materials-based Electrochemiluminescence emitters for sensing applications: Progress, challenges and perspectives".Coordination Chemistry Reviews 531(2025):216520.
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