A MnO2 nanosheet-assisted GSH detection platform using an iridium(III) complex as a switch-on luminescent probe

doi:10.1039/c6nr08357a

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	A MnO2 nanosheet-assisted GSH detection platform using an iridium(III) complex as a switch-on luminescent probe
	Dong, Zhen-Zhen 1; Lu, Lihua 1,2; Ko, Chung-Nga 1; Yang, Chao 3; Li, Shengnan 3; Lee, Ming-Yuen3 ; Leung, Chung-Hang3 ; Ma, Dik-Lung 1
	2017-04-14
Source Publication	NANOSCALE
ISSN	2040-3364
Volume	9 Issue:14 Pages:4677-4682
Abstract	A rapid and sensitive detection platform for GSH has been constructed by combining a MnO2 nanosheet with a luminescent iridium(III) complex [Ir(Cl-phq)2(Cl-phen)]+. The MnO2 nanosheet was prepared by using a facile one-step approach and was characterized by TEM. The luminescence intensity of the detection platform responded linearly with the GSH concentration from 1 to 200 mu M (R-2 = 0.9951), and the detection limit for GSH was 0.13 mu M. More importantly, practical application of the detection platform for visualizing the intracellular GSH distribution in living zebrafish has also been demonstrated.
DOI	10.1039/c6nr08357a
URL	View the original
Indexed By	SCIE
Language	英語English
WOS Research Area	Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics
WOS Subject	Chemistry, Multidisciplinary ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied
WOS ID	WOS:000398954800006
Publisher	ROYAL SOC CHEMISTRY
The Source to Article	WOS
Scopus ID	2-s2.0-85017327880
Fulltext Access	View Full-Text via DOI View Full-Text via Web of Science
Citation statistics
Document Type	Journal article
Collection	DEPARTMENT OF PHARMACEUTICAL SCIENCES Institute of Chinese Medical Sciences THE STATE KEY LABORATORY OF QUALITY RESEARCH IN CHINESE MEDICINE (UNIVERSITY OF MACAU)
Corresponding Author	Leung, Chung-Hang; Ma, Dik-Lung
Affiliation	1.Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, China 2.College of Chemistry and Pharmaceutical Sciences, Qingdao Agricultural University, Qingdao 266109, China 3.State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China
Corresponding Author Affilication	Institute of Chinese Medical Sciences
Recommended Citation GB/T 7714	Dong, Zhen-Zhen,Lu, Lihua,Ko, Chung-Nga,et al. A MnO2 nanosheet-assisted GSH detection platform using an iridium(III) complex as a switch-on luminescent probe[J]. NANOSCALE, 2017, 9(14), 4677-4682.
APA	Dong, Zhen-Zhen., Lu, Lihua., Ko, Chung-Nga., Yang, Chao., Li, Shengnan., Lee, Ming-Yuen., Leung, Chung-Hang., & Ma, Dik-Lung (2017). A MnO2 nanosheet-assisted GSH detection platform using an iridium(III) complex as a switch-on luminescent probe. NANOSCALE, 9(14), 4677-4682.
MLA	Dong, Zhen-Zhen,et al."A MnO2 nanosheet-assisted GSH detection platform using an iridium(III) complex as a switch-on luminescent probe".NANOSCALE 9.14(2017):4677-4682.

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