This research investigated how regulatory focus might influence trend-reversal predictions. We hypothesized that compared with promotion focus, prevention focus hinders sense of control, which in turn predicts more trend-reversal developments. Studies 1 and 3 revealed that participants expected trend-reversal developments to be more likely to occur when they focused on prevention than when they focused on promotion. Study 2 extended the findings by including a control condition, and revealed that participants expected trend-reversal developments to be more likely to occur in the prevention condition than in the promotion and control conditions. Studies 4 and 5 revealed that participants’ chronic prevention focus predicted a low sense of control (Study 4), and that promotion focus predicted a high sense of control (Studies 4 and 5). Furthermore, participants with a high sense of control expected trend-reversal developments to be less likely to occur. Thus, the results provided converging evidence for the hypothesis.