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Identification of Causal Mediation Models with an Unobserved Pre-treatment Confounder
He, Ping1; Wu, Zhenguo1; Zhang, Xiaohua Douglas2; Geng, Zhi1
2016
Source PublicationSTATISTICAL CAUSAL INFERENCES AND THEIR APPLICATIONS IN PUBLIC HEALTH RESEARCH
ISSN2199-0980
Pages241-262
Abstract

In this paper, we discuss identifiability of mediation, direct and indirect effects of treatment on outcome. The mediation effects are represented by a causal mediation model which includes an unobserved confounder (i.e., a common cause of the mediator and the outcome variable), and the direct and indirect effects are represented by the mediation effects. Without requiring the sequential ignorability assumption or the exclusion restriction assumption (i.e., the absence of direct effect of treatment on outcome), we require that only treatment is randomized and that the degree of equation nonlinearity for the treatment effect on the mediator is higher than that for the outcome. If the requirement of nonlinearity degree is not satisfied, we may use a covariate as an instrumental variable to improve the identifiability. In this paper, we focus on the identifiability of parameters, although, to illustrate our identifiability results, we describe estimation approaches. The simulations show good estimation performance by our approach compared to the standard mediation approach.

DOI10.1007/978-3-319-41259-7_13
Indexed BySCIE
Language英語English
WOS Research AreaHealth Care Sciences & Services ; Public, Environmental & Occupational Health ; Mathematical Methods In Social Sciences ; Mathematics
WOS SubjectHealth Care Sciences & Services ; Public, Environmental & Occupational Health ; Social Sciences, Mathematical Methods ; Statistics & Probability
WOS IDWOS:000411272500014
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Document TypeJournal article
CollectionFaculty of Health Sciences
Corresponding AuthorHe, Ping; Wu, Zhenguo; Zhang, Xiaohua Douglas; Geng, Zhi
Affiliation1.Peking Univ, Sch Math Sci, Beijing 100871, Peoples R China
2.Univ Macau, Fac Hlth Sci, Macau, Peoples R China
Corresponding Author AffilicationUniversity of Macau
Recommended Citation
GB/T 7714
He, Ping,Wu, Zhenguo,Zhang, Xiaohua Douglas,et al. Identification of Causal Mediation Models with an Unobserved Pre-treatment Confounder[J]. STATISTICAL CAUSAL INFERENCES AND THEIR APPLICATIONS IN PUBLIC HEALTH RESEARCH, 2016, 241-262.
APA He, Ping., Wu, Zhenguo., Zhang, Xiaohua Douglas., & Geng, Zhi (2016). Identification of Causal Mediation Models with an Unobserved Pre-treatment Confounder. STATISTICAL CAUSAL INFERENCES AND THEIR APPLICATIONS IN PUBLIC HEALTH RESEARCH, 241-262.
MLA He, Ping,et al."Identification of Causal Mediation Models with an Unobserved Pre-treatment Confounder".STATISTICAL CAUSAL INFERENCES AND THEIR APPLICATIONS IN PUBLIC HEALTH RESEARCH (2016):241-262.
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