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Cablinosides A and B, Two Glycosidic Phenylacetic Acid Derivatives from the Leaves of Pogostemon cablin
Xiao-Jun Huang1,2; Ping Li1; Zhi-Qi Yin3; Jin-Jian Lu1; Li-Gen Lin1; Ying Wang2; Wen-Cai Ye2; Qing-Wen Zhang1
2019-04-07
Source PublicationCHEMISTRY & BIODIVERSITY
ISSN1612-1872
Volume16Issue:5
Abstract

A pair of new glycosidic epimers, cablinosides A (1a) and B (1b) were isolated from the leaves of Pogostemon cablin. The structures with absolute configurations of 1a and 1b were elucidated by extensive NMR investigation, and quantum chemical CD calculations. The epimer mixture 1 showed moderate α‐glucosidase inhibitory activity and no significant cytotoxic activity against HepG2 cells.

KeywordPhytochemistry Pogostemon Cablin Cablinosides a And b Patchouli Cytotoxicity Inhibitors Structure Elucidation
DOI10.1002/cbdv.201900137
Indexed BySCIE
WOS Research AreaBiochemistry & Molecular Biology ; Chemistry
WOS SubjectBiochemistry & Molecular Biology ; Chemistry, Multidisciplinary
WOS IDWOS:000476956200023
Scopus ID2-s2.0-85065210451
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Document TypeJournal article
CollectionDEPARTMENT OF PHARMACEUTICAL SCIENCES
Institute of Chinese Medical Sciences
THE STATE KEY LABORATORY OF QUALITY RESEARCH IN CHINESE MEDICINE (UNIVERSITY OF MACAU)
Corresponding AuthorZhi-Qi Yin; Qing-Wen Zhang
Affiliation1.State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, P. R. China
2.Institute of Traditional Chinese Medicine and Natural Products & Guangdong Province Key Laboratory of Pharmacodynamic Constituents of Traditional Chinese Medicine and New Drugs Research, Jinan University, Guangzhou, 510632 P. R. China
3.Department of TCMs Pharmaceuticals, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, 210009 P.R. China
First Author AffilicationInstitute of Chinese Medical Sciences
Corresponding Author AffilicationInstitute of Chinese Medical Sciences
Recommended Citation
GB/T 7714
Xiao-Jun Huang,Ping Li,Zhi-Qi Yin,et al. Cablinosides A and B, Two Glycosidic Phenylacetic Acid Derivatives from the Leaves of Pogostemon cablin[J]. CHEMISTRY & BIODIVERSITY, 2019, 16(5).
APA Xiao-Jun Huang., Ping Li., Zhi-Qi Yin., Jin-Jian Lu., Li-Gen Lin., Ying Wang., Wen-Cai Ye., & Qing-Wen Zhang (2019). Cablinosides A and B, Two Glycosidic Phenylacetic Acid Derivatives from the Leaves of Pogostemon cablin. CHEMISTRY & BIODIVERSITY, 16(5).
MLA Xiao-Jun Huang,et al."Cablinosides A and B, Two Glycosidic Phenylacetic Acid Derivatives from the Leaves of Pogostemon cablin".CHEMISTRY & BIODIVERSITY 16.5(2019).
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