An iridium(III) complex/G-quadruplex ensemble for detection of ochratoxin A based on long-lifetime luminescent

doi:10.1016/j.ab.2019.06.005

UM > Institute of Chinese Medical Sciences

Residential College	false
Status	已發表Published
	An iridium(III) complex/G-quadruplex ensemble for detection of ochratoxin A based on long-lifetime luminescent
	Zhang, JT1 ; Kang, TS1 ; Wong, SY 2; Pei, RJ 3; Ma, DL 2; Leung, CH1
	2019-09
Source Publication	ANALYTICAL BIOCHEMISTRY
ISSN	0003-2697
Volume	580 Pages:49-55
Abstract	A G-quadruplex-based platform has been developed for the time-resolved monitoring of ochratoxin A (OTA). The simple platform displays good sensitivity for OTA with a detection limit of 40 nM via steady-state emission spectroscopy. Notably, the platform showed a detection limit of 10.8 nM via time-resolved emission spectroscopy (TRES), which is about 4 times more sensitive than steady-state mode. Moreover, the probe showed excellent selectivity for OTA over other mycotoxins. Furthermore, OTA was successfully detected in actual herbal plant extracts samples. Our platform is the first to detect OTA using TRES to distinguish between the target signals versus the auto-fluorescence of real samples. This platform shows improved detection speed, accuracy and sensitivity with simple operation, low cost, and no requirement for complicated pre-processing.
Keyword	Ota Herbal Plant Extracts Tres G-quadruplex
DOI	10.1016/j.ab.2019.06.005
Indexed By	SCIE
Language	英語English
WOS Research Area	Biochemistry & Molecular Biology ; Chemistry
WOS Subject	Biochemical Research Methods ; Biochemistry & Molecular Biology ; Chemistry, Analytical
WOS ID	WOS:000476576000007
Scopus ID	2-s2.0-85067188818
Fulltext Access	View Full-Text via DOI View Full-Text via Web of Science
Citation statistics
Document Type	Journal article
Collection	Institute of Chinese Medical Sciences
Corresponding Author	Pei, RJ; Ma, DL; Leung, CH
Affiliation	1.University of Macau, Inst Chinese Med Sci, State Key Lab Qual Res Chinese Med, Macau 999078, Peoples R China. 2.Hong Kong Baptist Univ, Dept Chem, Kowloon Tong, Hong Kong 999077, Peoples R China 3.Chinese Acad Sci, CAS Key Lab Nanobio Interface, Div Nanobiomed, Suzhou Inst Nanotech & Nanobion, Suzhou 215123, Peoples R China
First Author Affilication	University of Macau
Corresponding Author Affilication	University of Macau
Recommended Citation GB/T 7714	Zhang, JT,Kang, TS,Wong, SY,et al. An iridium(III) complex/G-quadruplex ensemble for detection of ochratoxin A based on long-lifetime luminescent[J]. ANALYTICAL BIOCHEMISTRY, 2019, 580, 49-55.
APA	Zhang, JT., Kang, TS., Wong, SY., Pei, RJ., Ma, DL., & Leung, CH (2019). An iridium(III) complex/G-quadruplex ensemble for detection of ochratoxin A based on long-lifetime luminescent. ANALYTICAL BIOCHEMISTRY, 580, 49-55.
MLA	Zhang, JT,et al."An iridium(III) complex/G-quadruplex ensemble for detection of ochratoxin A based on long-lifetime luminescent".ANALYTICAL BIOCHEMISTRY 580(2019):49-55.

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