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Dual stimuli-responsive bispillar[5]arene-based nanoparticles for precisely selective drug delivery in cancer cells
Cheng, Qian1; Teng, Kun-Xu2; Ding, Yuan-Fu1; Yue, Ludan1; Yang, Qing-Zheng2; Wang, Ruibing1
2019
Source PublicationCHEMICAL COMMUNICATIONS
ISSN1359-7345
Volume55Issue:16Pages:2340-2343
Abstract

Paclitaxel-loaded nanoparticles based on a bispillar[5]arene compound were successfully developed using a microemulsion method for the first time. The nanoparticles exhibited dual stimuli-responsiveness towards both spermine and glutathione, allowing precisely selective drug release in lung cancer cells that overexpress both stimuli.

DOI10.1039/c8cc09432b
Indexed BySCIE
Language英語English
WOS Research AreaChemistry
WOS SubjectChemistry, Multidisciplinary
WOS IDWOS:000459022300019
Scopus ID2-s2.0-85061860580
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Citation statistics
Document TypeJournal article
CollectionDEPARTMENT OF PHARMACEUTICAL SCIENCES
Institute of Chinese Medical Sciences
THE STATE KEY LABORATORY OF QUALITY RESEARCH IN CHINESE MEDICINE (UNIVERSITY OF MACAU)
Corresponding AuthorYang, Qing-Zheng; Wang, Ruibing
Affiliation1.State Key Laboratory of Quality Research in Chinese Medicine, Institute of ChineseMedical Sciences, University of Macau, Taipa, Macau SAR, China
2.Key Laboratory of Radiopharmaceuticals, Ministry of Education, College ofChemistry, Beijing Normal University, Beijing 100875, P. R. China
First Author AffilicationUniversity of Macau
Corresponding Author AffilicationUniversity of Macau
Recommended Citation
GB/T 7714
Cheng, Qian,Teng, Kun-Xu,Ding, Yuan-Fu,et al. Dual stimuli-responsive bispillar[5]arene-based nanoparticles for precisely selective drug delivery in cancer cells[J]. CHEMICAL COMMUNICATIONS, 2019, 55(16), 2340-2343.
APA Cheng, Qian., Teng, Kun-Xu., Ding, Yuan-Fu., Yue, Ludan., Yang, Qing-Zheng., & Wang, Ruibing (2019). Dual stimuli-responsive bispillar[5]arene-based nanoparticles for precisely selective drug delivery in cancer cells. CHEMICAL COMMUNICATIONS, 55(16), 2340-2343.
MLA Cheng, Qian,et al."Dual stimuli-responsive bispillar[5]arene-based nanoparticles for precisely selective drug delivery in cancer cells".CHEMICAL COMMUNICATIONS 55.16(2019):2340-2343.
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