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Targeting immune checkpoint B7-H3 antibody-chlorin e6 bioconjugates for spectroscopic photoacoustic imaging and photodynamic therapy
Zhu,Lipeng1; Liu,Jie1; Zhou,Guangyu1; Ng,Hoi Man2; Ang,Irene L.1; Ma,Guofang3; Liu,Yubin1; Yang,Shuo1; Zhang,Fengjuan1; Miao,Kai1; Poon,Terence C.W.1; Zhang,Xuanjun1; Yuan,Zhen1; Deng,Chu Xia1; Zhao,Qi1
2019
Source PublicationChemical Communications
ISSN1359-7345
Volume55Issue:95Pages:14255-14258
Abstract

In this study, we constructed bioconjugates of targeting immune checkpoint B7-H3 antibody and chlorin e6 to treat non-small cell lung cancer under the guidance of spectroscopic photoacoustic and fluorescence imaging. The B7-H3-Ce6 conjugates could display effective tumor diagnosis and therapy and provide a novel approach for immunotherapy.

DOI10.1039/c9cc06839b
URLView the original
Indexed BySCIE
Language英語English
WOS Research AreaChemistry
WOS SubjectChemistry, Multidisciplinary
WOS IDWOS:000500001300032
Scopus ID2-s2.0-85075671639
Fulltext Access
Citation statistics
Document TypeJournal article
CollectionDEPARTMENT OF BIOMEDICAL SCIENCES
Faculty of Health Sciences
DEPARTMENT OF PUBLIC HEALTH AND MEDICINAL ADMINISTRATION
Corresponding AuthorZhao,Qi
Affiliation1.Cancer Centre,Institute of Translational Medicine,Faculty of Health Sciences,University of Macau,999078,Macao
2.Clinical Laboratory,Kiang Wu Hospital,999078,Macao
3.Geriatric Department,China-Japan Union Hospital of Jilin University,Changchun Jilin Province,130033,China
First Author AffilicationCancer Centre
Corresponding Author AffilicationCancer Centre
Recommended Citation
GB/T 7714
Zhu,Lipeng,Liu,Jie,Zhou,Guangyu,et al. Targeting immune checkpoint B7-H3 antibody-chlorin e6 bioconjugates for spectroscopic photoacoustic imaging and photodynamic therapy[J]. Chemical Communications, 2019, 55(95), 14255-14258.
APA Zhu,Lipeng., Liu,Jie., Zhou,Guangyu., Ng,Hoi Man., Ang,Irene L.., Ma,Guofang., Liu,Yubin., Yang,Shuo., Zhang,Fengjuan., Miao,Kai., Poon,Terence C.W.., Zhang,Xuanjun., Yuan,Zhen., Deng,Chu Xia., & Zhao,Qi (2019). Targeting immune checkpoint B7-H3 antibody-chlorin e6 bioconjugates for spectroscopic photoacoustic imaging and photodynamic therapy. Chemical Communications, 55(95), 14255-14258.
MLA Zhu,Lipeng,et al."Targeting immune checkpoint B7-H3 antibody-chlorin e6 bioconjugates for spectroscopic photoacoustic imaging and photodynamic therapy".Chemical Communications 55.95(2019):14255-14258.
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