Bioactive Limonoids and Triterpenoids from the Fruits of Melia azedarach

doi:10.1021/acs.jnatprod.9b01151

UM > THE STATE KEY LABORATORY OF QUALITY RESEARCH IN CHINESE MEDICINE (UNIVERSITY OF MACAU)

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	Bioactive Limonoids and Triterpenoids from the Fruits of Melia azedarach
	Song,Min1 ; Zhang,Jian 2; Chan,Ging1 ; Hou,Ying1 ; Chen,Xiu Ping1 ; Zhang,Xiao Qi 2; Ye,Wen Cai 2; Zhang,Qing Wen1
	2020-11-30
Source Publication	Journal of Natural Products
ISSN	0163-3864
Volume	83 Issue:12 Pages:3502-3510
Abstract	Nine new limonoids, meliazedarines A-I (1-9), seven known analogues (10-16), and five known triterpenoids (17-21) were isolated from the fruits of Melia azedarach. Their structures were determined by analysis of 1D and 2D NMR, HRESIMS, X-ray diffraction, and electronic circular dichroism (ECD) data. Compound 7 showed significant cytotoxicity against the HCT116 cell line with IC50 values of 0.3 ± 0.1 μM.
DOI	10.1021/acs.jnatprod.9b01151
URL	View the original
Indexed By	SCIE ; IC
Language	英語English
WOS Research Area	Plant Sciences ; Pharmacology & Pharmacy
WOS Subject	Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy 4.05
WOS ID	WOS:000603402900002
Scopus ID	2-s2.0-85097828233
Fulltext Access	View Full-Text via DOI View Full-Text via Web of Science View Full-Text via Scopus
Citation statistics
Document Type	Journal article
Collection	THE STATE KEY LABORATORY OF QUALITY RESEARCH IN CHINESE MEDICINE (UNIVERSITY OF MACAU) Institute of Chinese Medical Sciences
Corresponding Author	Zhang,Qing Wen
Affiliation	1.State Key Laboratory of Quality Research in Chinese Medicine,Institute of Chinese Medical Sciences,University of Macau,Macao 2.Guangdong Provincial Engineering Research Center for Modernization of TCM,College of Pharmacy,Jinan University,Guangzhou,510632,China
First Author Affilication	Institute of Chinese Medical Sciences
Corresponding Author Affilication	Institute of Chinese Medical Sciences
Recommended Citation GB/T 7714	Song,Min,Zhang,Jian,Chan,Ging,et al. Bioactive Limonoids and Triterpenoids from the Fruits of Melia azedarach[J]. Journal of Natural Products, 2020, 83(12), 3502-3510.
APA	Song,Min., Zhang,Jian., Chan,Ging., Hou,Ying., Chen,Xiu Ping., Zhang,Xiao Qi., Ye,Wen Cai., & Zhang,Qing Wen (2020). Bioactive Limonoids and Triterpenoids from the Fruits of Melia azedarach. Journal of Natural Products, 83(12), 3502-3510.
MLA	Song,Min,et al."Bioactive Limonoids and Triterpenoids from the Fruits of Melia azedarach".Journal of Natural Products 83.12(2020):3502-3510.

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