UGT73F17, a new glycosyltransferase from Glycyrrhiza uralensis, catalyzes the regiospecific glycosylation of pentacyclic triterpenoids

doi:10.1039/c8cc04215b

UM > Institute of Chinese Medical Sciences

Residential College	false
Status	已發表Published
	UGT73F17, a new glycosyltransferase from Glycyrrhiza uralensis, catalyzes the regiospecific glycosylation of pentacyclic triterpenoids
	He, Junbin 1; Chen, Kuan 1; Hu, Zhi-min 1; Li, Kai 1; Song, Wei 1; Yu, Li-yan 2,3; Leung, Chung-Hang4 ; Ma, Dik-Lung 5; Qiao, Xue 1; Ye, Min 1
	2018-08-11
Source Publication	CHEMICAL COMMUNICATIONS
ISSN	1359-7345
Volume	54 Issue:62 Pages:8594-8597
Abstract	The regiospecific glycosylation of pentacyclic triterpenoids by UGT73F17, a new glycosyltransferase from Glycyrrhiza uralensis, is highlighted. UGT73F17 exhibited strict substrate specificity toward the carboxyl group at C-30/C-29 of pentacyclic triterpenoids, and showed high promiscuity to sugar donors. UGT73F17 represents the first identified triterpenoid 30/29-O-glycosyltransferase, and could be used as an effective biocatalyst to synthesize glycosyl ester saponins.
DOI	10.1039/c8cc04215b
URL	View the original
Indexed By	SCIE ; IC
Language	英語English
WOS Research Area	Chemistry
WOS Subject	Chemistry, Multidisciplinary
WOS ID	WOS:000440432600006
Publisher	ROYAL SOC CHEMISTRY
The Source to Article	WOS
Scopus ID	2-s2.0-85050887413
Fulltext Access	View Full-Text via DOI View Full-Text via Web of Science
Citation statistics
Document Type	Journal article
Collection	Institute of Chinese Medical Sciences
Corresponding Author	Ye, Min
Affiliation	1.Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, 38 Xueyuan Rd, Beijing 100191, Peoples R China 2.Chinese Acad Med Sci, Inst Med Biotechnol, Beijing 100050, Peoples R China 3.Peking Union Med Coll, Beijing 100050, Peoples R China 4.University of Macau, Inst Chinese Med Sci, State Key Lab Qual Res Chinese Med, Macau, Peoples R China 5.Hong Kong Baptist Univ, Dept Chem, Kowloon Tong, Hong Kong, Peoples R China
Recommended Citation GB/T 7714	He, Junbin,Chen, Kuan,Hu, Zhi-min,et al. UGT73F17, a new glycosyltransferase from Glycyrrhiza uralensis, catalyzes the regiospecific glycosylation of pentacyclic triterpenoids[J]. CHEMICAL COMMUNICATIONS, 2018, 54(62), 8594-8597.
APA	He, Junbin., Chen, Kuan., Hu, Zhi-min., Li, Kai., Song, Wei., Yu, Li-yan., Leung, Chung-Hang., Ma, Dik-Lung., Qiao, Xue., & Ye, Min (2018). UGT73F17, a new glycosyltransferase from Glycyrrhiza uralensis, catalyzes the regiospecific glycosylation of pentacyclic triterpenoids. CHEMICAL COMMUNICATIONS, 54(62), 8594-8597.
MLA	He, Junbin,et al."UGT73F17, a new glycosyltransferase from Glycyrrhiza uralensis, catalyzes the regiospecific glycosylation of pentacyclic triterpenoids".CHEMICAL COMMUNICATIONS 54.62(2018):8594-8597.

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