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Prevalence of suicide attempts in individuals with schizophrenia: A meta-analysis of observational studies
Lu,Li1; Dong,Min1; Zhang,Ling2; Zhu,Xiao Min3; Ungvari,Gabor S.4,5,6; Ng,Chee H.7; Wang,Gang2; Xiang,Yu Tao1
2019
Source PublicationEpidemiology and Psychiatric Sciences
ISSN2045-7960
Abstract

AimsSuicide attempt is an important indicator of suicide and potential future mortality. However, the prevalence of suicide attempts has been inconsistent across studies. This meta-analysis aimed to examine the prevalence of suicide attempts in individuals with schizophrenia and associated correlates.MethodsRelevant publications in Embase, PsycINFO, PubMed, Web of science and Cochrane were systematically searched. Data on the prevalence of suicide attempts in individuals with schizophrenia were pooled using a random-effects model.ResultsThirty-five studies with 16 747 individuals with schizophrenia were included. The pooled lifetime prevalence of suicide attempts was 26.8% (95% CI 22.1-31.9%; I = 97.0%), while the 1-year prevalence, 1-month prevalence and the prevalence of suicide attempts from illness onset were 3.0% (95% CI 2.3-3.7%; I = 95.6%), 2.7% (95% CI 2.1-3.4%; I = 78.5%) and 45.9% (95% CI 42.1-49.9%; I = 0), respectively. Earlier age of onset (Q = 4.38, p = 0.04), high-income countries (Q = 53.29, p < 0.001), North America and Europe and Central Asia (Q = 32.83, p < 0.001) were significantly associated with a higher prevalence of suicide attempts.ConclusionsSuicide attempts are common in individuals with schizophrenia, especially those with an early age of onset and living in high-income countries and regions. Regular screening and effective preventive measures should be implemented as part of the clinical care.

KeywordMeta-analysis Schizophrenia Suicide Attempt
DOI10.1017/S2045796019000313
URLView the original
Language英語English
WOS IDWOS:000585066900014
Scopus ID2-s2.0-85066970130
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Document TypeJournal article
CollectionFaculty of Health Sciences
Corresponding AuthorXiang,Yu Tao
Affiliation1.Unit of Psychiatry,Institute of Translational Medicine,Faculty of Health Sciences,University of Macau,Macao
2.National Clinical Research Centre for Mental Disorders,Beijing Key Laboratory of Mental Disorders,Beijing Anding Hospital,Advanced Innovation Centre for Human Brain Protection,Capital Medical University,Beijing,China
3.Institute of Mental Health,Suzhou Psychiatric Hospital,Affiliated Guangji Hospital of Soochow University,Jiangsu,China
4.Division of Psychiatry,University of Western Australia Medical School,Perth,Australia
5.Graylands Hospital,Perth,Australia
6.University of Notre Dame Australia,Marian Centre,Perth,Australia
7.Department of Psychiatry,University of Melbourne,Melbourne,Australia
First Author AffilicationFaculty of Health Sciences
Corresponding Author AffilicationFaculty of Health Sciences
Recommended Citation
GB/T 7714
Lu,Li,Dong,Min,Zhang,Ling,et al. Prevalence of suicide attempts in individuals with schizophrenia: A meta-analysis of observational studies[J]. Epidemiology and Psychiatric Sciences, 2019.
APA Lu,Li., Dong,Min., Zhang,Ling., Zhu,Xiao Min., Ungvari,Gabor S.., Ng,Chee H.., Wang,Gang., & Xiang,Yu Tao (2019). Prevalence of suicide attempts in individuals with schizophrenia: A meta-analysis of observational studies. Epidemiology and Psychiatric Sciences.
MLA Lu,Li,et al."Prevalence of suicide attempts in individuals with schizophrenia: A meta-analysis of observational studies".Epidemiology and Psychiatric Sciences (2019).
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