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A self-delivery DNA nanoprobe for reliable microRNA imaging in live cells by aggregation induced red-shift-emission
Chen,Zhe1,2; Lu,Jingxiong2,3; Xiao,Fan2; Huang,Yishun2; Zhang,Xuanjun1; Tian,Leilei2
2020
Source PublicationCHEMICAL COMMUNICATIONS
ISSN1359-7345
Volume56Issue:10Pages:1501-1504
Abstract

A new DNA nanoprobe based on a Y-shape and pyrene-modified DNA self-assembly is developed to sensitively and specifically detect microRNA through a pyrene excimer-monomer switch. Exhibiting the capability of self-delivery and resistance to nuclease degradation, the nanoprobe has been successfully applied for microRNA imaging in live cells.

DOI10.1039/c9cc08093g
URLView the original
Indexed BySCIE
Language英語English
WOS Research AreaChemistry
WOS SubjectChemistry, Multidisciplinary
WOS IDWOS:000511328200003
PublisherROYAL SOC CHEMISTRYTHOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND
Scopus ID2-s2.0-85079022719
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Citation statistics
Document TypeJournal article
CollectionCentre of Reproduction, Development and Aging
Faculty of Health Sciences
Cancer Centre
Corresponding AuthorZhang,Xuanjun; Tian,Leilei
Affiliation1.Cancer Centre,Centre of Reproduction,Development and Aging,Faculty of Health Sciences,University of Macau,Taipa,999078,Macao
2.Department of Materials Science and Engineering,Southern University of Science and Technology,Shenzhen, Guangdong,1088 Xueyuan Blvd. Nanshan District,518055,China
3.Institute of Medi-X,Academy for Advanced Interdisciplinary Studies,Southern University of Science and Technology,Shenzhen, Guangdong,1088 Xueyuan Blvd. Nanshan District,518055,China
First Author AffilicationCancer Centre
Corresponding Author AffilicationCancer Centre
Recommended Citation
GB/T 7714
Chen,Zhe,Lu,Jingxiong,Xiao,Fan,et al. A self-delivery DNA nanoprobe for reliable microRNA imaging in live cells by aggregation induced red-shift-emission[J]. CHEMICAL COMMUNICATIONS, 2020, 56(10), 1501-1504.
APA Chen,Zhe., Lu,Jingxiong., Xiao,Fan., Huang,Yishun., Zhang,Xuanjun., & Tian,Leilei (2020). A self-delivery DNA nanoprobe for reliable microRNA imaging in live cells by aggregation induced red-shift-emission. CHEMICAL COMMUNICATIONS, 56(10), 1501-1504.
MLA Chen,Zhe,et al."A self-delivery DNA nanoprobe for reliable microRNA imaging in live cells by aggregation induced red-shift-emission".CHEMICAL COMMUNICATIONS 56.10(2020):1501-1504.
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