This paper presents a hydrodynamic-flow-enhanced rapid mixing technique on DMF platforms. By applying a low frequency actuation signal to a stationary droplet on a single-electrode mixing chamber, the induced internal hydrodynamic flow and droplet boundary oscillation can effectively improve the mixing time with negligible change in droplet temperature (< 0.1℃). Reliable mixing efficiency improvement independent on the solute concentrations is also validated as benefitting from the mechanical oscillation of the stationary droplet, rendering it as a promising tool for practical applications of chemosynthesis, bioanalysis, drug delivery, and synthesis of nucleic acid.