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A review of recent advances in robotic cell microinjection
Ziqiang Chi1; Qingsong Xu1; Limin Zhu2
2020-01-06
Source PublicationIEEE Access
ISSN2169-3536
Volume8Pages:8520-8532
Abstract

Cell microinjection is a direct and effective way to transfer external materials into the cell. In the field of modern biomedicine, cell microinjection is very important, no matter in genetics, reproductive health, tumor therapy or others related research directions. Traditional manual cell microinjection has the disadvantages of low efficiency and low survival rate. In contrast, robotic cell microinjection can achieve precise and effective cell microinjection, and can be used in the injection of large quantities of cells. This paper reviews recent advances in robotic cell microinjection technologies. It summarizes the main approaches of key technologies and their advantages and disadvantages, such as cell identification, cell holding, precise positioning platform, cell injection strategy, sensors in cell microinjection, and cell modeling. The conclusion of the investigation is that the robotic cell microinjection has achieved remarkable results and still has great potential for further development. It is expected to be widely used in biomedicine and other fields to realize convenient, fast, and efficient microinjection operations of large number of individual cells.

KeywordCell Holding Cell Identification Cell Modeling Injection Strategy Precise Displacement Platform Robotic Cell Microinjection Sensors In Cell microInjection
DOI10.1109/ACCESS.2020.2964305
URLView the original
Indexed BySCIE
Language英語English
WOS Research AreaComputer Science ; Engineering ; Telecommunications
WOS SubjectComputer Science, Information Systems ; Engineering, Electrical & Electronic ; Telecommunications
WOS IDWOS:000525422700143
Scopus ID2-s2.0-85078253337
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Citation statistics
Document TypeJournal article
CollectionDEPARTMENT OF ELECTROMECHANICAL ENGINEERING
Corresponding AuthorQingsong Xu
Affiliation1.Department of Electromechanical Engineering,Faculty of Science and Technology,University of Macau,Macao
2.State Key Laboratory of Mechanical System and Vibration,School of Mechanical Engineering,Shanghai Jiao Tong University,Shanghai,200240,China
First Author AffilicationFaculty of Science and Technology
Corresponding Author AffilicationFaculty of Science and Technology
Recommended Citation
GB/T 7714
Ziqiang Chi,Qingsong Xu,Limin Zhu. A review of recent advances in robotic cell microinjection[J]. IEEE Access, 2020, 8, 8520-8532.
APA Ziqiang Chi., Qingsong Xu., & Limin Zhu (2020). A review of recent advances in robotic cell microinjection. IEEE Access, 8, 8520-8532.
MLA Ziqiang Chi,et al."A review of recent advances in robotic cell microinjection".IEEE Access 8(2020):8520-8532.
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